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EC Number
Inhibitors
Commentary
Structure
3.6.4.6
bafilomycin A
-
3.6.4.6
Ist1
subunit of endosomal sorting complex required for the transport III, maximal inhibition at 0.008 or less mM
3.6.4.6
more
phosphorylation by Pctaire1 attenuates the hexamerization of NSF
3.6.4.6
more
binding of substrates to the central pore of the Vps4 ATPase is autoinhibited by the microtubule interacting and trafficking (MIT) domain, substrate engagement is autoinhibited by the Vps4p-MIT-domain and the inhibition is relieved by binding of either Type 1 or Type 2 MIM elements, which bind the Vps4p MIT domain through different interfaces
3.6.4.6
N-ethylmaleimide
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3.6.4.6
TAT-NSF700
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