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Information on EC 3.4.22.69 - SARS coronavirus main proteinase

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The enzyme appears in viruses and cellular organisms
Synonyms
main protease, 3cl protease, sars-cov 3clpro, sars-cov 3cl protease, coronavirus main protease, sars coronavirus main protease, sars 3c-like proteinase, sars-cov main protease, tgev mpro, sars 3clpro, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
TSAVLQ-/-SGFRK-NH2 and SGVTFQ-/-!GKFKK the two peptides corresponding to the two self-cleavage sites of the SARS 3C-like proteinase are the two most reactive peptide substrates. The enzyme exhibits a strong preference for substrates containing Gln at P1 position and Leu at P2 position.
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