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Information on EC 2.7.7.85 - diadenylate cyclase

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EC Tree
     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.85 diadenylate cyclase
IUBMB Comments
Cyclic di-3',5'-adenylate is a bioactive molecule produced by some bacteria and archaea, which may function as a secondary signalling molecule . The intracellular bacterial pathogen Listeria monocytogenes secretes it into the host's cytosol, where it triggers a cytosolic pathway of innate immunity .
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Word Map
The expected taxonomic range for this enzyme is: Bacteria
Synonyms
dna integrity scanning protein, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 ATP = 2 diphosphate + cyclic di-3',5'-adenylate
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