EC Number   |
Metals/Ions |
Reference |
|---|
   2.7.7.85 | Ca2+ |
the enzyme is strictly dependent on divalent cations, activity in presence of 10 mM Ca2+ is 10.6% compared to activity in presence of 10 mM Mg2+ |
722145 |
| 2.7.7.85 | Co2+ |
activates slightly, can only partly substitute for Mn2+. Co2+ is coordinated by the phosphate moiety and the carboxylate group of Glu224 as well as the carboxylate group of Asp171 and the imidazole ring nitrogen of His170 of the symmetry-related subunit |
761490 |
| 2.7.7.85 | Co2+ |
or Mn2+, required. Maximum activity at 0.75-10 mM |
738669 |
| 2.7.7.85 | Mg2+ |
- |
723182 |
| 2.7.7.85 | Mg2+ |
best activator, maximum activity at 10 mM |
738291 |
| 2.7.7.85 | Mg2+ |
required |
761397, 761401 |
| 2.7.7.85 | Mg2+ |
the enzyme is strictly dependent on divalent cations, optimal activity at 10 mM Mg2+ |
722145 |
| 2.7.7.85 | Mn2+ |
activates, required for catalysis |
761490 |
| 2.7.7.85 | Mn2+ |
or Co2+, required. Maximum activity at 0.75-5 mM |
738669 |
| 2.7.7.85 | Mn2+ |
required, specific for |
761855 |
