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Literature summary for 2.7.7.85 extracted from

  • Woodward, J.; Lavarone, A.; Portnoy, D.
    C-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response (2010), Science, 328, 1703-1705.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 ATP Listeria monocytogenes the intracellular bacterial pathogen Listeria monocytogenes secretes cyclic di-3',5'-adenylate into the cytosol of the host, where it triggers a cytosolic pathway of innate immunity 2 diphosphate + cyclic di-3',5'-adenylate
-
 ?

Organism

Organism UniProt Comment Textmining
Listeria monocytogenes Q8Y5E4
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ATP
-
 Listeria monocytogenes 2 diphosphate + cyclic di-3',5'-adenylate
-
 ?
2 ATP the intracellular bacterial pathogen Listeria monocytogenes secretes cyclic di-3',5'-adenylate into the cytosol of the host, where it triggers a cytosolic pathway of innate immunity Listeria monocytogenes 2 diphosphate + cyclic di-3',5'-adenylate
-
 ?

Synonyms

Synonyms Comment Organism
dacA
-
 Listeria monocytogenes
Lmo2120 protein
-
 Listeria monocytogenes

General Information

General Information Comment Organism
physiological function the intracellular bacterial pathogen Listeria monocytogenes secretes cyclic di-3',5'-adenylate into the cytosol of the host, where it triggers a cytosolic pathway of innate immunity Listeria monocytogenes