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EC Explorer

EC 2.3.1.208 Details
EC number
2.3.1.208
Accepted name
4-hydroxycoumarin synthase
Reaction
malonyl-CoA + 2-hydroxybenzoyl-CoA = 2 CoA + 4-hydroxycoumarin + CO2
Other name(s)
BIS2, BIS3
Systematic name
malonyl-CoA:2-hydroxybenzoyl-CoA malonyltransferase
Comment
The enzyme, a polyketide synthase, can also accept benzoyl-CoA as substrate, which it condenses with 3 malonyl-CoA molecules to form 3,5-dihydroxybiphenyl (cf. EC 2.3.1.177, biphenyl synthase) [1].
History
created 2012
EC Tree
2.3.1.55 created 1976, deleted 1999
2.3.1.120 created 1990, deleted 1992
2.3.1.124 created 1990, deleted 1992