Any feedback?
Please rate this page
(ecexplorer.php)
(0/150)

BRENDA support

EC Explorer

EC 2.3.1.156 Details
EC number
2.3.1.156
Accepted name
phloroisovalerophenone synthase
Reaction
(1) isovaleryl-CoA + 3 malonyl-CoA = 4 CoA + 3 CO2 + phlorisovalerophenone;;(2) isobutyryl-CoA + 3 malonyl-CoA = 4 CoA + 3 CO2 + phlorisobutyrophenone
Other name(s)
valerophenone synthase, 3-methyl-1-(trihydroxyphenyl)butan-1-one synthase, acylphloroglucinol synthase, isovaleryl-CoA:malonyl-CoA acyltransferase
Systematic name
acyl-CoA:malonyl-CoA acyltransferase
Comment
Closely related to EC 2.3.1.74, naringenin-chalcone synthase. Also acts on isobutyryl-CoA as substrate to give phlorisobutyrophenone. The products are intermediates in the biosynthesis of the bitter acids in hops (Humulus lupulus) and glucosides in strawberry (Fragaria X ananassa). It is also able to generate naringenin chalcone from 4-coumaroyl-CoA.
History
created 2000
EC Tree
2.3.1.55 created 1976, deleted 1999
2.3.1.120 created 1990, deleted 1992
2.3.1.124 created 1990, deleted 1992