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EC 2.3.1.164 Details
EC number
2.3.1.164
Accepted name
isopenicillin-N N-acyltransferase
Reaction
phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate
Other name(s)
acyl-coenzyme A:isopenicillin N acyltransferase, isopenicillin N:acyl-CoA: acyltransferase
Systematic name
acyl-CoA:isopenicillin N N-acyltransferase
CAS registry number
54576-90-8
Comment
Proceeds by a two stage mechanism via 6-aminopenicillanic acid. Different from EC 3.5.1.11, penicillin amidase.
History
created 2002
EC Tree
2.3.1.55 created 1976, deleted 1999
2.3.1.120 created 1990, deleted 1992
2.3.1.124 created 1990, deleted 1992