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Information on EC 2.3.1.164 - isopenicillin-N N-acyltransferase

for references in articles please use BRENDA:EC2.3.1.164
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IUBMB Comments
Proceeds by a two stage mechanism via 6-aminopenicillanic acid. Different from EC 3.5.1.11, penicillin amidase.
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The enzyme appears in viruses and cellular organisms
Synonyms
6-aminopenicillanate acyltransferase, 6-aminopenicillanic acid acyltransferase, 6-aminopenicillinanic acid phenylacetyltransferase, 6-aminopenicillinanic acylase, aatA, aatB, acyl coA:isopenicillin N-acyltransferase, acyl coenzyme A: isopenicillin N acyltransferase, acyl coenzyme A:6-aminopenicillanic acid acyltransferase, acyl-CoA:6-aminopenicillanate acyltransferase, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate
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