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EC 2.3.1.308 Details
EC number
2.3.1.308
Accepted name
tubulin N-terminal N-acetyltransferase NAT9
Reaction
acetyl-CoA + an N-terminal-L-methionyl-[tubulin] = an N-terminal-Nα-acetyl-L-methionyl-[tubulin] + CoA
Other name(s)
NAT9 (gene name), microtubule-associated N-acetyltransferase NAT9
Systematic name
acetyl-CoA:N-terminal-Met-[tubulin] Met-Nα-acetyltransferase
Comment
The enzyme, characterized from the fruit fly (Drosophila melanogaster), acetylates the N-terminal of both α- and β-tubulin. The enzyme acts cotranslationally, and can't act on a preformed tubulin α/β heterodimer.
History
created 2022
EC Tree
2.3.1.55 created 1976, deleted 1999
2.3.1.120 created 1990, deleted 1992
2.3.1.124 created 1990, deleted 1992