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Information on EC 2.3.1.208 - 4-hydroxycoumarin synthase

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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.208 4-hydroxycoumarin synthase
IUBMB Comments
The enzyme, a polyketide synthase, can also accept benzoyl-CoA as substrate, which it condenses with 3 malonyl-CoA molecules to form 3,5-dihydroxybiphenyl (cf. EC 2.3.1.177, biphenyl synthase) .
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The enzyme appears in viruses and cellular organisms
Synonyms
biphenyl synthase, BIS, BIS1, BIS2, BIS3, More, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
malonyl-CoA + 2-hydroxybenzoyl-CoA = 2 CoA + 4-hydroxycoumarin + CO2
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PATHWAY SOURCE
PATHWAYS
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