3.5.4.9: methenyltetrahydrofolate cyclohydrolase

This is an abbreviated version!
For detailed information about methenyltetrahydrofolate cyclohydrolase, go to the full flat file.

Reaction

Synonyms

5,10-CH+-H4PteGlu cyclohydrolase, 5,10-CH+-THF cyclohydrolase, 5,10-CH=H4 folate synthetase, 5,10-methenyl-H4folate cyclohydrolase, 5,10-methenyl-THF cyclohydrolase, 5,10-methenyltetrahydrofolate cyclohydrolase, 5,10-methenyltetrahydrofolate cyclohydrolase/5,10-methylene tetrahydrofolate dehydrogenase, 5,10-Methenyltetrahydrofolate synthetase, 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase, ADE3, bifunctional methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase, bifunctional N5,N10-methylene-H4F dehydrogenase/N5,N10-methenyl-H4F cyclohydrolase, CH+-THF cyclohydrolase, CHF4CH, Citrovorum factor cyclodehydrase, cyclohydrolase, dehydrogenasse-cyclohydrolase-synthetase, DHCH, DHCH 1, DHCH 2, DHCH1, FchA, FolD, formyl-methenyl-methylenetetrahydrofolate synthetase (combined), methenyl-H4F cyclohydrolase, methenyl-tetrahydrofolate cyclohydrolase, methenyl-THF cyclohydrolase, methenylH4F cyclohydrolase, methenyltetrahydrofolate cyclohydrolase, methenyltetrahydrofolate dehydrogenase/cyclohydrolase, methylene tetrahydrofolate dehydrogenase/cyclohydrolase, methylene-tetrahydrofolate dehydrogenase/cyclohydrolase, methyleneH4folate cyclohydrolase, methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase, methylenetetrahydrofolate dehydrogenase/cyclohydrolase, methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase, methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase, MIS1, More, mosquito cyclohydrolase, MTHFD1, MTHFD2, MTHFD2L, MTHFDC, N5,N10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase, N5,N10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase, N5,N10-methylenetetrahydrofolate dehydrogenase/N5,N10-methenyltetrahydrofolate cyclohydrolase, NAD-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.4 In cyclic amidines

                3.5.4.9 methenyltetrahydrofolate cyclohydrolase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
7	Activating Compound
49967	AA Sequence
4	Application
1	CAS Registry Number
21	Cloned(Commentary)
6	Cofactor
8	Crystallization (Commentary)
486	Disease/ Diagnostics
2	Expression
8	General Information
3	General Stability
8	IC50 Value
35	Inhibitors
5	kcat/KM [mM/s]
5	Ki Value [mM]
64	KM Value [mM]
28	Localization
37	Molecular Weight [Da]
166	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
172	Organism
21	Pathway
86	PDB ID
15	pH Optimum
3	pH Range
36	Protein Variants
27	Purification (Commentary)
3	Reaction
5	Reaction Type
155	Reference
79	Source Tissue
101	Specific Activity [micromol/min/mg]
8	Storage Stability
185	Substrates and Products (Substrate)
30	Subunits
85	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
3	Temperature Stability [°C]
13	Turnover Number [1/s]

Storage Stability

print visible entries

print all entries

Storage Stability on EC 3.5.4.9 - methenyltetrahydrofolate cyclohydrolase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Storage Stability Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-20°C purified enzyme in 50% glycerol, 95% active after 6 months

Escherichia coli

-

209731

-20°C, 25% glycerol, 20% cyclohydrolase activity remains after 1 month

Pisum sativum

-

209737

-20°C, loses 15% activity in 1 day, 50% in 5 days and 70% in 30 days

Sus scrofa

-

209729

-80°C, 50 mM potassium phosphate, 30% glycerol buffer, stable for over 1 month

Homo sapiens

-

209736

0°C, relatively unstable, losing 40% activity in 1 day and 75% in 4 days

Sus scrofa

-

209729

4°C, 25% glycerol, 60% cyclohydrolase activity remains after 1 month

Pisum sativum

-

209737

5°C, 50 mM phosphate buffer, pH 7.0, stable for at least 1 week

Clostridium formicaceticum

-

209719, 209721