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3.5.1.2: glutaminase

This is an abbreviated version!
For detailed information about glutaminase, go to the full flat file.

Word Map on EC 3.5.1.2

Reaction

L-glutamine
+
H2O
=
L-glutamate
 +
NH3

Synonyms

AnsB, AoGls, GA, GAB, GAC, GahB, GLA, GLNase, GLS, GLS1, GLS2, GlsA, glutaminase, glutaminase 1, glutaminase 2, glutaminase A, glutaminase B, glutaminase C, glutaminase I, glutaminase K, glutaminase L, glutaminase-1, glutaminase-2, glutaminase-B, glutamine amidohydrolase, glutamine aminohydrolase, glutamine deamidating enzyme, K-glutaminase, KAG, KGA, kidney-type glutaminase, kidney-type-glutaminase, L-glutaminase, L-glutamine amidohydrolase, LAG, LGA, liver-type glitaminase, liver-type glutaminase, Mglu, Micrococcus glutaminase Mglu, Micrococcus luteus K-3-type glutaminase, mitochondrial glutaminase, N-PAG, neuroblastoma glutaminase, neuroblastoma PAG, Nit 2, nitrilase 2, omega-amidase, PAG, PDX2, phosphate activated glutaminase, phosphate-activated glutaminase, phosphate-activated L-glutamine amidohydrolase, salt-tolerant glutaminase, YaaE

ECTree

     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.2 glutaminase

Turnover Number

Turnover Number on EC 3.5.1.2 - glutaminase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
17.5
2-oxo-glutaramate
-
pH 8.5, 30°C
0.87 - 1.15
2-oxo-succinamate
134.5
5-methoxy-2,5-dioxopentanoic acid
-
pH 7.2, 30°C
36
gamma-ethyl glutamate
-
-
14
gamma-glutamyl hydrazide
-
-
296
gamma-glutamyl methoxyamide
-
-
8
gamma-glutamyl methylamide
-
-
212
gamma-glutamyl-hydroxamate
-
-
645
gamma-methyl glutamate
-
-
300
gamma-thioethyl glutamate
-
-
1260
gamma-thiomethyl glutamate
-
-
1270
Gln
-
-
5080
Glu
-
-
4.1 - 8.8
Glutaramate
4790
Gly-Gln
-
at pH 9.0 and 50°C
4.83 - 1606
L-asparagine
0.222 - 6249
L-glutamine
2 - 2.8
succinamate
additional information
additional information
-
effect of pH on turnover number
-