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3.1.1.43: alpha-amino-acid esterase

This is an abbreviated version!
For detailed information about alpha-amino-acid esterase, go to the full flat file.

Word Map on EC 3.1.1.43

Reaction

an alpha-amino acid ester
+
H2O
=
an alpha-amino acid
 +
an alcohol

Synonyms

AEH, alpha-amino acid ester esterase, alpha-amino acid ester hydrolase, biphenyl hydrolase-like protein, BPH, esterase, alpha-amino acid, VACVase, valacyclovirase

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.43 alpha-amino-acid esterase

KM Value

KM Value on EC 3.1.1.43 - alpha-amino-acid esterase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.009
4-carbamimidamidobenzyl L-isoleucinate
-
pH 7.4, 37°C
0.207
4-carbamimidamidobenzyl L-phenylalaninate
-
pH 7.4, 37°C
0.046
4-carbamimidamidobenzyl L-valinate
-
pH 7.4, 37°C
0.011
4-hydroxy-D-phenylglycine methyl ester
-
pH 6.0, 30°C, recombinant enzyme
5.08
7-amino-3-deacetoxycephalosporanic acid
-
-
0.0026 - 2.6
amoxicillin
0.0006 - 1
ampicillin
0.00034 - 1.7
cefadroxil
0.0017 - 0.00196
cefaloglycin
0.001
cefatrizine
-
below, hydrolysis, pH 6.4, 25°C, recombinant enzyme
0.00179
cefradine
Pseudomonas melanogenum
-
pH 6.0, 37°C
0.00035 - 2.99
cephalexin
1.1
D-2-nitro-5-[(phenylglycyl)amino]benzoic acid
30°C, pH 6.2
63 - 292
D-4-hydroxyphenylglycine methyl ester
40.9
D-alanine methyl ester
-
-
8.26
D-alpha-phenylglycine methyl ester
-
-
0.013 - 13
D-phenylglycine amide
0.0026 - 7
D-phenylglycine methyl ester
2.6
ethyl DL-alpha-amino-n-butyrate
-
-
5
glycine ethyl ester
-
-
0.8
L-valine methyl ester
-
-
4.3
methyl D-alpha-aminophenylacetate
-
-
32.2
methyl DL-alpha-aminoisobutyrate
-
-
24
methyl L-alpha-aminophenylacetate
-
-
0.099
phenylalanine benzyl ester
-
pH 7.4, 37°C, recombinant enzyme
6.7
phenylalanine ethyl ester
-
pH 7.4, 37°C, recombinant enzyme
5.14
phenylalanine methyl ester
-
pH 7.4, 37°C, recombinant enzyme
0.207
phenylalanine [3-(hydroxymethyl)phenyl]guanidine
-
pH 7.4, 37°C, recombinant enzyme
0.5
S-benzyl-L-cysteine ethyl ester
-
-
0.00006 - 0.068
valacyclovir
0.0019
valganciclovir
-
pH 7.4, 37°C, recombinant enzyme
0.014
valine 4-nitrobenzyl ester
-
pH 7.4, 37°C, recombinant enzyme
0.06
valine benzyl ester
-
pH 7.4, 37°C, recombinant enzyme
1.81
valine [3-(aminomethyl)phenyl]guanidine
-
pH 7.4, 37°C, recombinant enzyme
0.046
valine [3-(hydroxymethyl)phenyl]guanidine
-
pH 7.4, 37°C, recombinant enzyme
additional information
additional information
-