3.1.1.43: alpha-amino-acid esterase

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For detailed information about alpha-amino-acid esterase, go to the full flat file.

Reaction

Synonyms

AEH, alpha-amino acid ester esterase, alpha-amino acid ester hydrolase, biphenyl hydrolase-like protein, BPH, esterase, alpha-amino acid, VACVase, valacyclovirase

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.1 Carboxylic-ester hydrolases

                3.1.1.43 alpha-amino-acid esterase

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Results	in table
1	Activating Compound
20	AA Sequence
24	Application
1	CAS Registry Number
12	Cloned(Commentary)
4	Crystallization (Commentary)
3	Disease/ Diagnostics
57	General Information
1	General Stability
15	Inhibitors
35	kcat/KM [mM/s]
76	KM Value [mM]
1	Localization
3	Metals/Ions
23	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
22	Organic Solvent Stability
63	Organism
36	PDB ID
27	pH Optimum
2	pH Range
2	pH Stability
9	pI Value
1	Posttranslational Modification
24	Protein Variants
12	Purification (Commentary)
2	Reaction
4	Reaction Type
59	Reference
10	Source Tissue
19	Specific Activity [micromol/min/mg]
266	Substrates and Products (Substrate)
34	Subunits
89	Synonyms
1	Systematic Name
23	Temperature Optimum [°C]
2	Temperature Range [°C]
3	Temperature Stability [°C]
54	Turnover Number [1/s]

pH Optimum

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pH Optimum on EC 3.1.1.43 - alpha-amino-acid esterase

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pH OPTIMUM

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

5.5 - 6

Pseudomonas melanogenum

-

strain KY3987, ampicillin synthesis

729021

6

Pseudomonas melanogenum

-

ampicillin synthesis and hydrolysis

729021

6 - 6.25

Acidovorax avenae

-

assay at

730436

6 - 6.4

Xanthomonas citri

-

synthesis and hydrolysis of cephalexin and D-phenylglycine methyl ester

729021

6 - 6.5

6 entries

6.1 - 6.2

Xanthomonas sp.

-

synthesis and hydrolysis of cephalexin and D-phenylglycine methyl ester

729021

6.2

2 entries

6.4

Xanthomonas citri

-

hydrolysis and acyl group transfer

80934

6.5

4 entries

6.8

Xanthomonas campestris

-

ampicillin hydrolysis

729021

7.4

3 entries

7.4 - 8

Homo sapiens

-

valacyclovir hydrolysis in vitro

729021

7.5

2 entries

7.6

Bacillus mycoides

-

hydrolysis of phenylalanine methylester

651785

9

Stenotrophomonas maltophilia

A0A2Z6IAJ2

-

749442

6 - 6.5

Acetobacter pasteurianus

-

-

729021

6 - 6.5

Gluconobacter oxydans

-

-

729021

6 - 6.5

Mycoplana dimorpha

-

-

729021

6 - 6.5

Protaminobacter alboflavus

-

-

729021

6 - 6.5

Pseudomonas danceae

-

-

729021

6 - 6.5

Xanthomonas oryzae

-

-

729021

6.2

Acetobacter pasteurianus

-

cephalexin synthesis and hydrolysis

729021

6.2

Acidovorax avenae

-

assay at

729461

6.5

Acidovorax avenae

-

cephalexin hydrolysis

729021

6.5

Pseudomonas melanogenum

-

assay at

729021

6.5

Pseudomonas melanogenum

-

strain KY3987, synthesis of amoxicillin, ampicillin, cephalexin, cefaloglycin, and cefadroxil

729021

6.5

Pseudomonas melanogenum

-

strain KY8540, synthesis of amoxicillin, ampicillin, cephalexin, cefaloglycin, and cefadroxil

729021

7.4

Homo sapiens

-

assay at

716273

7.4

Homo sapiens

-

activity assay

693224

7.4

Homo sapiens

-

valacyclovir hydrolysis in vitro

729021

7.5

Flavobacterium sp.

-

ampicillin synthesis and hydrolysis, no hydrolysis of penicillin G

729021

7.5

Rattus norvegicus

-

valacyclovir hydrolysis in vitro

729021