1.3.8.7: medium-chain acyl-CoA dehydrogenase

This is an abbreviated version, for detailed information about medium-chain acyl-CoA dehydrogenase, go to the full flat file.

Reaction

a medium-chain acyl-CoA
+
electron-transfer flavoprotein
=
a medium-chain trans-2,3-dehydroacyl-CoA
+
reduced electron-transfer flavoprotein

Synonyms

ACAD-9, ACADM, ACD, acyl CoA dehydrogenase, acyl coenzyme A dehydrogenase, acyl dehydrogenase, acyl-CoA dehydrogenase, acyl-CoA dehydrogenase-9, dehydrogenase, acyl coenzyme A, EC 1.3.2.2, FadE, fatty acyl coenzyme A dehydrogenase, fatty-acyl-CoA dehydrogenase, general ACAD, general acyl CoA dehydrogenase, LCAD, LipB, MCAD, MCADH, medium chain acyl-CoA dehydrogenase, medium chain-specific acyl-CoA oxidase, medium-chain acyl CoA dehydrogenase, medium-chain acyl-CoA dehydrogenase, medium-chain acyl-coenzyme A dehydrogenase, medium-chain coenzyme A dehydrogenase, pMCAD, PP_1893, PP_2039, PP_2048, PP_2437

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.8 With a flavin as acceptor
                1.3.8.7 medium-chain acyl-CoA dehydrogenase

KM Value

KM Value on EC 1.3.8.7 - medium-chain acyl-CoA dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0023
4-cis,7-cis-decadienoyl-CoA
-
-
0.004
4-cis-Decenoyl-CoA
-
-
0.0029
4-decynoyl-CoA
-
-
0.003
5-cis-decenoyl-CoA
-
-
0.0021
6-cis-decenoyl-CoA
-
-
0.002
all-cis-4,7,10,13-hexadecatetraenoyl-CoA
-
-
0.001 - 0.007
beta(2-furyl)propionyl-CoA
0.0091
beta-(2-Furyl)propionyl-CoA
-
-
0.0084 - 0.45
Butanoyl-CoA
0.00714
butyryl-CoA
-
-
0.016 - 0.038
crotonyl-CoA
-
hydratase reaction, value depending on pH
0.0007 - 0.05
decanoyl-CoA
0.0025 - 0.05
Dodecanoyl-CoA
0.0034 - 0.0045
electron transfer flavoprotein
0.0003 - 0.01
electron transferring flavoprotein
0.0024
FAD
-
-
0.055
ferricenium hexafluorophosphate
-
-
0.0099 - 0.069
ferrocenium hexafluorophosphate
0.014 - 0.0144
furylpropionyl-CoA
0.001 - 0.002
hexadecanoyl-CoA
0.0014 - 0.0216
Hexanoyl-CoA
0.00049 - 0.01
indolepropionyl-CoA
0.00021
linoleoyl-CoA
-
-
0.0011
Octanoyl 3'-dephospho-CoA
-
-
0.00928
Octanoyl-1,N6-etheno-CoA
-
-
0.00084 - 1.47
Octanoyl-CoA
0.107
octanoyl-pantetheine
-
-
0.00007
palmitoleoyl-CoA
-
-
0.0008 - 0.023
palmitoyl-CoA
0.0396
pentanoyl-CoA
-
-
1.67
phenazine methosulfate
-
-
0.0023 - 0.0057
tetradecanoyl-CoA
0.01
tetradecenoyl-CoA
-
-
-
0.0563
valeryl-CoA
-
-
0.0426 - 0.061
[4-(dimethylamino)phenyl]propionyl-CoA
additional information
additional information
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-
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