Reference on EC 1.3.8.7 - medium-chain acyl-CoA dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Matsubara, Y.; Indo, Y.; Naito, E.; Ozasa, H.; Glassberg, R.; Vockley, J.; Ikeda, Y.; Kraus, J.; Tanaka, K.
Molecular cloning and nucleotide sequence of cDNAs encoding the precursors of rat long chain acyl-coenzyme A, short chain acyl-coenzyme A, and isovaleryl-coenzyme A dehydrogenases. Sequence homology of four enzymes of the acyl-CoA dehydrogenase family
J. Biol. Chem.
264
16321-16331
1989
Rattus norvegicus
Manually annotated by BRENDA team
Finocchiaro, G.; Ito, M.; Tanaka, K.
Purification and properties of short chain acyl-CoA, medium chain acyl-CoA, and isovaleryl-CoA dehydrogenases from human liver
J. Biol. Chem.
262
7982-7989
1987
Homo sapiens
Manually annotated by BRENDA team
Ikeda, Y.; Dabrowski, C.; Tanaka, K.
Separation and properties of five distinct acyl-CoA dehydrogenases from rat liver mitochondria. Identification of a new 2-methyl branched chain acyl-CoA dehydrogenase
J. Biol. Chem.
258
1066-1076
1983
Rattus norvegicus
Manually annotated by BRENDA team
Ikeda, Y.; Tanaka, K.
Selective inactivation of various acyl-CoA dehydrogenases by (methylenecyclopropyl)acetyl-CoA
Biochim. Biophys. Acta
1038
216-221
1990
Rattus norvegicus
Manually annotated by BRENDA team
Ikeda, Y.; Okamura-Ikeda, K.; Tanaka, K.
Spectroscopic analysis of the interaction of rat liver short-chain, medium-chain, and long-chain acyl coenzyme A dehydrogenases with acyl coenzyme A substrates
Biochemistry
24
7192-7199
1985
Rattus norvegicus
Manually annotated by BRENDA team
Okamura-Ikeda, K.; Ikeda, Y.; Tanaka, K.
An essential cysteine residue located in the vicinity of the FAD-binding site in short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria
J. Biol. Chem.
260
1338-1345
1985
Rattus norvegicus
Manually annotated by BRENDA team
Ikeda, Y.; Hine, D.G.; Okamura-Ikeda, K.; Tanaka, K.
Mechanism of action of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases. Direct evidence for carbanion formation as an intermediate step using enzyme-catalyzed C-2 proton/deuteron exchange in the absence of C-3 exchange
J. Biol. Chem.
260
1326-1337
1985
Rattus norvegicus
Manually annotated by BRENDA team
Ikeda, Y.; Okamura-Ikeda, K.; Tanaka, K.
Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the apoenzyme to the holoenzyme
J. Biol. Chem.
260
1311-1325
1985
Rattus norvegicus
Manually annotated by BRENDA team
Ghisla, S.; Thorpe, C.; Massey, V.
Mechanistic studies with general acyl-CoA dehydrogenase and butyryl-CoA dehydrogenase: evidence for the transfer of the beta-hydrogen to the flavin N(5)-position as a hydride
Biochemistry
23
3154-3161
1984
Sus scrofa
Manually annotated by BRENDA team
Dommes, V.; Kunau, W.H.
Purification and properties of acyl coenzyme A dehydrogenases from bovine liver. Formation of 2-trans,4-cis-decadienoyl coenzyme A
J. Biol. Chem.
259
1789-1797
1984
Bos taurus
Manually annotated by BRENDA team
Furuta, S.; Miyazawa, S.; Hashimoto, T.
Purification and properties of rat liver acyl-CoA dehydrogenases and electron transfer flavoprotein
J. Biochem.
90
1739-1750
1981
Rattus norvegicus
Manually annotated by BRENDA team
Davidson, B.; Schulz, H.
Separation, properties, and regulation of acyl coenzyme A dehydrogenases from bovine heart and liver
Arch. Biochem. Biophys.
213
155-162
1982
Bos taurus
Manually annotated by BRENDA team
Baldwin, J.E.; Ostrander, R.L.; Simon, C.D.; Widdison, W.C.
Stereospecific inactivation of the general acyl-CoA dehydrogenase from pig kidney by (R)-(-)-(methylenecyclopropyl)acetyl-CoA and (S)-(+)-(methylenecyclopropyl)acetyl-CoA
J. Am. Chem. Soc.
112
2021-2022
1990
Sus scrofa
-
Manually annotated by BRENDA team
Lenn, N.D.; Stankovich, M.T.; Liu, H.W.
Regulation of the redox potential of general acyl-CoA dehydrogenase by substrate binding
Biochemistry
29
3709-3715
1990
Sus scrofa
Manually annotated by BRENDA team
Lehmann, T.C.; Hale, D.E.; Bhala, A.; Thorpe, C.
An acyl-coenzyme A dehydrogenase assay utilizing the ferricenium ion
Anal. Biochem.
186
280-284
1990
Sus scrofa
Manually annotated by BRENDA team
Lai, M.; Liu, H.
Inactivation of general acyl-CoA dehydrogenase by enatiomerically pure (methylencyclopropyl)acetyl-CoA and its implication for this enzyme-catalyzed reaction
J. Am. Chem. Soc.
112
4034-4035
1990
Sus scrofa
-
Manually annotated by BRENDA team
Zhou, J.Z.; Thorpe, C.
Inactivation of two-electron reduced medium chain acyl-CoA dehydrogenase by 2-octynoyl-CoA
Arch. Biochem. Biophys.
271
261-269
1989
Sus scrofa
Manually annotated by BRENDA team
Kim, J.J.P.; Wu, J.
Structure of the medium-chain acyl-CoA dehydrogenase from pig liver mitochondria at 3-A resolution
Proc. Natl. Acad. Sci. USA
85
6677-6681
1988
Sus scrofa
Manually annotated by BRENDA team
Powell, P.J.; Thorpe, C.
2-Octynoyl coenzyme A is a mechanism-based inhibitor of pig kidney medium-chain acyl coenzyme A dehydrogenase: isolation of the target peptide
Biochemistry
27
8022-8028
1988
Sus scrofa
Manually annotated by BRENDA team
Schopfer, L.M.; Massey, V.; Ghisla, S.; Thorpe, C.
Oxidation-reduction of general acyl-CoA dehydrogenase by the butyryl-CoA/crotonyl-CoA couple. A new investigation of the rapid reaction kinetics
Biochemistry
27
6599-6611
1988
Sus scrofa
Manually annotated by BRENDA team
Lau, S.M.; Brantley, R.K.; Thorpe, C.
The reductive half-reaction in Acyl-CoA dehydrogenase from pig kidney: studies with thiaoctanoyl-CoA and oxaoctanoyl-CoA analogues
Biochemistry
27
5089-5095
1988
Sus scrofa
Manually annotated by BRENDA team
Lau, S.M.; Thorpe, C.
The nature of enzyme-substrate complexes in acyl-coenzyme A dehydrogenases
Arch. Biochem. Biophys.
262
293-297
1988
Sus scrofa
Manually annotated by BRENDA team
Frerman, F.E.
Acyl-CoA dehydrogenases, electron transfer flavoprotein and electron transfer flavoprotein dehydrogenase
Biochem. Soc. Trans.
16
416-418
1988
Mammalia
Manually annotated by BRENDA team
Matsubara, Y.; Kraus, J.P.; Ozasa, H.; Glassberg, R.; Finocchiaro, G.; Ikeda, Y.; Mole, J.; Rosenberg, L.E.; Tanaka, K.
Molecular cloning and nucleotide sequence of cDNA encoding the entire precursor of rat liver medium chain acyl coenzyme A dehydrogenase
J. Biol. Chem.
262
10104-10108
1987
Rattus norvegicus
Manually annotated by BRENDA team
Chalmers, R.A.; English, N.
Fatty acid oxidation in cultured skin fibroblasts from patients with inherited disorders of fatty acid metabolism: studies on the specificity of acyl-CoA dehydrogenases
Biochem. Soc. Trans.
15
489-491
1987
Homo sapiens
-
Manually annotated by BRENDA team
Powell, P.J.; Lau, S.M.; Killian, D.; Thorpe, C.
Interaction of acyl coenzyme A substrates and analogues with pig kidney medium-chain acyl-coA dehydrogenase
Biochemistry
26
3704-3710
1987
Sus scrofa
Manually annotated by BRENDA team
Matsubara, Y.; Kraus, J.P.; Yang-Feng, T.L.; Francke, U.; Rosenberg, L.E.; Tanaka, K.
Molecular cloning of cDNAs encoding rat and human medium-chain acyl-CoA dehydrogenase and assignment of the gene to human chromosome 1
Proc. Natl. Acad. Sci. USA
83
6543-6547
1986
Homo sapiens
Manually annotated by BRENDA team
Lau, S.M.; Powell, P.; Buettner, H.; Ghisla, S.; Thorpe, C.
Medium-chain acyl coenzyme A dehydrogenase from pig kidney has intrinsic enoyl coenzyme A hydratase activity
Biochemistry
25
4184-4189
1986
Sus scrofa
Manually annotated by BRENDA team
O'Connell, M.; Henry, S.; Shapiro, L.
Fatty acid degradation in Caulobacter crescentus
J. Bacteriol.
168
49-54
1986
Caulobacter vibrioides
Manually annotated by BRENDA team
Gustafson, W.G.; Feinberg, B.A.; McFarland, J.T.
Energetics of beta-oxidation. Reduction potentials of general fatty acyl-CoA dehydrogenase, electron transfer flavoprotein, and fatty acyl-CoA substrates
J. Biol. Chem.
261
7733-7741
1986
Sus scrofa
Manually annotated by BRENDA team
Rojas, C.; Schmidt, J.; Lee, M.Y.; Gustafson, W.G.; McFarland, J.T.
Structure-function correlation of fatty acyl-CoA dehydrogenase and fatty acyl-CoA oxidase
Biochemistry
24
2947-2954
1985
Sus scrofa
Manually annotated by BRENDA team
Wenz, A.; Ghisla, S.; Thorpe, C.
Studies with general acyl-CoA dehydrogenase from pig kidney. Inactivation by a novel type of suicide inhibitor, 3,4-pentadienoyl-CoA
Eur. J. Biochem.
147
553-560
1985
Sus scrofa
Manually annotated by BRENDA team
Stabenau, H.; Winkler, U.; Säftel, W.
Enzymes of beta-oxidation in different types of algal microbodies
Plant Physiol.
75
531-533
1984
Eremosphaera viridis, Mougeotia sp.
Manually annotated by BRENDA team
Madden, M.; Lau, S.M.; Thorpe, C.
The influence of oxidation-reduction state on the kinetic stability of pig kidney general acyl-CoA dehydrogenase and other flavoproteins
Biochem. J.
224
577-580
1984
Sus scrofa
Manually annotated by BRENDA team
Beckmann, J.D.; Frerman, F.E.
The effects of pH, ionic strength, and chemical modifications on the reaction of electron transfer flavoprotein with an acyl coenzyme A dehydrogenase
J. Biol. Chem.
258
7563-7569
1983
Sus scrofa
Manually annotated by BRENDA team
Ishii, H.; Ishii, S.; Kazama, M.; Suga, T.
Peroxisomal fatty acyl-coenzyme A oxidation in chicken liver
Arch. Biochem. Biophys.
226
484-491
1983
Gallus gallus
Manually annotated by BRENDA team
Thorpe, C.; Massey, V.
Flavin analogue studies of pig kidney general acyl-CoA dehydrogenase
Biochemistry
22
2972-2978
1983
Sus scrofa
Manually annotated by BRENDA team
McFarland, J.T.; Lee, M.Y.; Reinsch, J.; Raven, W.
Reactions of beta-(2-furyl)propionyl coenzyme A with general fatty acyl-CoA dehydrogenase
Biochemistry
21
1224-1229
1982
Sus scrofa
Manually annotated by BRENDA team
Beckmann, J.D.; Frerman, F.E.; McKean, M.C.
Inhibition of general acyl CoA dehydrogenase by electron transfer flavoprotein semiquinone
Biochem. Biophys. Res. Commun.
102
1290-1294
1981
Sus scrofa
Manually annotated by BRENDA team
Hall, C.L.
Acyl-CoA dehydrogenases from pig liver mitochondria
Methods Enzymol.
71
375-385
1981
Sus scrofa
Manually annotated by BRENDA team
Thorpe, C.
Acyl-CoA dehydrogenase from pig kidney
Methods Enzymol.
71
366-374
1981
Sus scrofa
Manually annotated by BRENDA team
Mizzer, J.P.; Thorpe, C.
Stabilization of the red semiquinone form of pig kidney general acyl-CoA dehydrogenase by acyl coenzyme A derivatives
Biochemistry
20
4965-4970
1981
Sus scrofa
Manually annotated by BRENDA team
Mayer, E.J.; Thorpe, C.
A method for resolution of general acyl-coenzyme A dehydrogenase apoprotein
Anal. Biochem.
116
227-229
1981
Sus scrofa
Manually annotated by BRENDA team
Frerman, F.E.; Miziorko, H.M.; Beckmann, J.D.
Enzyme-activated inhibitors, alternate substrates, and a dead end inhibitor of the general acyl-CoA dehydrogenase
J. Biol. Chem.
255
11192-11198
1980
Sus scrofa
Manually annotated by BRENDA team
Frerman, F.E.; Mielke, D.; Huhta, K.
The functional role of carboxyl residues in an acyl-CoA dehydrogenase
J. Biol. Chem.
255
2199-2202
1980
Sus scrofa
Manually annotated by BRENDA team
Frerman, F.E.; Kim, J.J.P.; Huhta, K.; McKean, M.C.
Properties of the general acyl-CoA dehydrogenase from pig liver
J. Biol. Chem.
255
2195-2198
1980
Sus scrofa
Manually annotated by BRENDA team
Hall, C.L.
Acyl-CoA dehydrogenases and electron-transferring flavoprotein
Methods Enzymol.
53
502-518
1978
Bos taurus, Sus scrofa
Manually annotated by BRENDA team
McKean, M.C.; Frerman, F.E.; Mielke, D.M.
General acyl-CoA dehydrogenase from pig liver. Kinetic and binding studies
J. Biol. Chem.
254
2730-2735
1979
Sus scrofa
Manually annotated by BRENDA team
Thorpe, C.; Matthews, R.G.; Williams, C.H.
Acyl-coenzyme A dehydrogenase from pig kidney. Purification and properties
Biochemistry
18
331-337
1979
Sus scrofa
Manually annotated by BRENDA team
Engel, P.C.
Fatty acyl-coenzyme A dehydrogenases
Biochem. Soc. Trans.
6
76-80
1978
Mammalia
Manually annotated by BRENDA team
Hall, C.L.; Heijkenskjöld, L.; Bartfai, T.; Ernster, L.; Kamin, H.
Acyl coenzyme A dehydrogenases and electron-transferring flavoprotein from beef hart mitochondria
Arch. Biochem. Biophys.
177
402-414
1976
Bos taurus
Manually annotated by BRENDA team
Hall, C.L.; Kamin, H.
The purification and some properties of electron transfer flavoprotein and general fatty acyl coenzyme A dehydrogenase from pig liver mitochondria
J. Biol. Chem.
250
3476-3486
1975
Sus scrofa
Manually annotated by BRENDA team
Thorpe, C.; Ciardelli, T.L.; Stewart, C.J.; Wieland, T.
Interaction of long-chain acyl-CoA analogs with pig kidney general acyl-CoA dehydrogenase
Eur. J. Biochem.
118
279-282
1981
Sus scrofa
Manually annotated by BRENDA team
Mizzer, J.P.; Thorpe, C.
An essential methionine in pig kidney general acyl-CoA dehydrogenase
Biochemistry
19
5500-5504
1980
Sus scrofa
Manually annotated by BRENDA team
Kim, J.J.; Wang, M.; Paschke, R.
Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate
Proc. Natl. Acad. Sci. USA
90
7523-7527
1993
Sus scrofa
Manually annotated by BRENDA team
Bross, P.; Jensen, T.G.; Andresen, B.S.; Kjeldsen, M.; Nandy, A.; Kolvraa, S.; Ghisla, S.; Rasched, I.; Bolund, L.; Gregersen, N.
Characterization of wild-type human medium-chain acyl-CoA dehydrogenase (MCAD) and mutant enzymes present in MCAD-deficient patients by two-dimensional gel electrophoresis: evidence for post-translational modification of the enzyme
Biochem. Med. Metab. Biol.
52
36-44
1994
Homo sapiens
Manually annotated by BRENDA team
Peterson, K.L.; Sergienko, E.E.; Wu, Y.; Kumar, N.R.; Strauss, A.W.; Oleson, A.E.; Muhonen, W.W.; Shabb, J.B.; Srivastava, D.K.
Recombinant human liver medium-chain acyl-CoA dehydrogenase: purification, characterization, and the mechanism of interactions with functionally diverse C8-CoA molecules
Biochemistry
34
14942-14953
1995
Homo sapiens, Sus scrofa
Manually annotated by BRENDA team
Lee, H.J.; Wang, M.; Paschke, R.; Nandy, A.; Ghisla, S.; Kim, J.J.
Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity
Biochemistry
35
12412-12420
1996
Homo sapiens, Sus scrofa
Manually annotated by BRENDA team
Nandy, A.; Kieweg, V.; Kraeutle, F.G.; Vock, P.; Kuechler, B.; Bross, P.; Kim, J.J.P.; Rasched, I.; Ghisla, S.
Medium-long-chain chimeric human acyl-CoA dehydrogenase: medium-chain enzyme with the active center base arrangement of long-chain acyl-CoA dehydrogenase
Biochemistry
35
12402-12411
1996
Homo sapiens
Manually annotated by BRENDA team
Kieweg, V.; Krautle, F.G.; Nandy, A.; Engst, S.; Vock, P.; Abdel-Ghany, A.G.; Bross, P.; Gregersen, N.; Rasched, I.; Strauss, A.; Ghisla, S.
Biochemical characterization of purified, human recombinant Lys304-->Glu medium-chain acyl-CoA dehydrogenase containing the common disease-causing mutation and comparison with the normal enzyme
Eur. J. Biochem.
246
548-556
1997
Homo sapiens, Sus scrofa
Manually annotated by BRENDA team
Eder, M.; Krautle, F.; Dong, Y.; Vock, P.; Kieweg, V.; Kim, J.J.; Strauss, A.W.; Ghisla, S.
Characterization of human and pig kidney long-chain-acyl-CoA dehydrogenases and their role in beta-oxidation
Eur. J. Biochem.
245
600-607
1997
Homo sapiens
Manually annotated by BRENDA team
Qin, L.; Srivastava, D.K.
Energetics of two-step binding of a chromophoric reaction product, trans-3-indoleacryloyl-CoA, to medium-chain acyl-coenzyme-A dehydrogenase
Biochemistry
37
3499-3508
1998
Sus scrofa
Manually annotated by BRENDA team
Kuchler, B.; Abdel-Ghany, A.G.; Bross, P.; Nandy, A.; Rasched, I.; Ghisla, S.
Biochemical characterization of a variant human medium-chain acyl-CoA dehydrogenase with a disease-associated mutation localized in the active site
Biochem. J.
337
225-230
1999
Homo sapiens
Manually annotated by BRENDA team
Baltazar, M.F.; Dickinson, F.M.; Ratledge, C.
Oxidation of medium-chain acyl-CoA esters by extracts of Aspergillus niger: enzymology and characterization of intermediates by HPLC
Microbiology
145
271-278
1999
Aspergillus niger
Manually annotated by BRENDA team
Lamm, T.R.; Kohls, T.D.; Saenger, A.K.; Stankovich, M.T.
Comparison of ligand polarization and enzyme activation in medium- and short-chain acyl-coenzyme A dehydrogenase-novel analog complexes
Arch. Biochem. Biophys.
409
251-261
2003
Sus scrofa
Manually annotated by BRENDA team
Gopalan, K.V.; Srivastava, D.K.
Beyond the proton abstracting role of Glu-376 in medium-chain acyl-CoA dehydrogenase: influence of Glu-376-->Gln substitution on ligand binding and catalysis
Biochemistry
41
4638-4648
2002
Homo sapiens
Manually annotated by BRENDA team
Wu, J.; Bell, A.F.; Luo, L.; Stephens, A.W.; Stankovich, M.T.; Tonge, P.J.
Probing hydrogen-bonding interactions in the active site of medium-chain acyl-CoA dehydrogenase using Raman spectroscopy
Biochemistry
42
11846-11856
2003
Sus scrofa
Manually annotated by BRENDA team
Nasser, I.; Mohsen, A.W.; Jelesarov, I.; Vockley, J.; Macheroux, P.; Ghisla, S.
Thermal unfolding of medium-chain acyl-CoA dehydrogenase and iso(3)valeryl-CoA dehydrogenase: study of the effect of genetic defects on enzyme stability
Biochim. Biophys. Acta
1690
22-32
2004
Homo sapiens
Manually annotated by BRENDA team
O'Reilly, L.; Bross, P.; Corydon, T.J.; Olpin, S.E.; Hansen, J.; Kenney, J.M.; McCandless, S.E.; Frazier, D.M.; Winter, V.; Gregersen, N.; Engel, P.C.; Andresen, B.S.
The Y42H mutation in medium-chain acyl-CoA dehydrogenase, which is prevalent in babies identified by MS/MS-based newborn screening, is temperature sensitive
Eur. J. Biochem.
271
4053-4063
2004
Rattus norvegicus
Manually annotated by BRENDA team
Nishina, Y.; Sato, K.; Tamaoki, H.; Tanaka, T.; Setoyama, C.; Miura, R.; Shiga, K.
Molecular mechanism of the drop in the pKa of a substrate analog bound to medium-chain acyl-CoA dehydrogenase: implications for substrate activation
J. Biochem.
134
835-842
2003
Sus scrofa
Manually annotated by BRENDA team
Katagiri, H.; Asano, T.; Yamada, T.; Aoyama, T.; Fukushima, Y.; Kikuchi, M.; Kodama, T.; Oka, Y.
Acyl-coenzyme A dehydrogenases are localized on GLUT4-containing vesicles via association with insulin-regulated aminopeptidase in a manner dependent on its dileucine motif
Mol. Endocrinol.
16
1049-1059
2002
Mus musculus
Manually annotated by BRENDA team
Zeng, J.; Li, D.
Expression and purification of His-tagged rat mitochondrial medium-chain acyl-CoA dehydrogenase wild-type and Arg256 mutant proteins
Protein Expr. Purif.
37
472-478
2004
Rattus norvegicus
Manually annotated by BRENDA team
Froemming, M.K.; Sames, D.
Fluoromorphic Substrates for fatty acid metabolism: Highly sensitive probes for mammalian medium-chain acyl-CoA dehydrogenase
Angew. Chem.
45
637-642
2006
Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Zeng, J.; Deng, G.; Yu, W.; Li, D.
Inactivation of medium-chain acyl-CoA dehydrogenase by oct-4-en-2-ynoyl-CoA
Bioorg. Med. Chem. Lett.
16
1445-1448
2006
Rattus norvegicus
Manually annotated by BRENDA team
Ensenauer, R.; He, M.; Willard, J.M.; Goetzman, E.S.; Corydon, T.J.; Vandahl, B.B.; Mohsen, A.W.; Isaya, G.; Vockley, J.
Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial beta-oxidation of unsaturated fatty acids
J. Biol. Chem.
280
32309-32316
2005
Homo sapiens
Manually annotated by BRENDA team
Ruswandi, S.; Kitani, K.; Akimitsu, K.; Tsuge, T.; Shiraishi, T.; Yamamoto, M.
Structural analysis of cosmid clone pcAFT-2 carrying AFT10-1 encoding an acyl-CoA dehydrogenase involved in AF-toxin production in the strawberry pathotype of Alternaria alternata
J. Gen. Plant Pathol.
71
107-116
2005
Alternaria alternata
-
Manually annotated by BRENDA team
Harrison, F.H.; Harwood, C.S.
The pimFABCDE operon from Rhodopseudomonas palustris mediates dicarboxylic acid degradation and participates in anaerobic benzoate degradation
Microbiology
151
1963-1974
2005
Actinoplanes friuliensis, Rhodopseudomonas palustris
Manually annotated by BRENDA team
Maegawa, G.H.; Poplawski, N.K.; Andresen, B.S.; Olpin, S.E.; Nie, G.; Clarke, J.T.; Teshima, I.
Interstitial deletion of 1p22.2p31.1 and medium-chain acyl-CoA dehydrogenase deficiency in a patient with global developmental delay
Am. J. Med. Genet. A
146A
1581-1586
2008
Homo sapiens
Manually annotated by BRENDA team
Nichols, M.J.; Saavedra-Matiz, C.A.; Pass, K.A.; Caggana, M.
Novel mutations causing medium chain acyl-CoA dehydrogenase deficiency: under-representation of the common c.985 A > G mutation in the New York state population
Am. J. Med. Genet. A
146A
610-619
2008
Homo sapiens
Manually annotated by BRENDA team
Gradinaru, R.; Schowen, R.; Ghisla, S.
Solvent isotope effects in reactions of human medium-chain acyl-CoA dehydrogenase active site mutants
Biochemistry
46
2497-2509
2007
Homo sapiens
Manually annotated by BRENDA team
Zeng, J.; Liu, Y.; Wu, L.; Li, D.
Mutation of Tyr375 to Lys375 allows medium-chain acyl-CoA dehydrogenase to acquire acyl-CoA oxidase activity
Biochim. Biophys. Acta
1774
1628-1634
2007
Rattus norvegicus
Manually annotated by BRENDA team
Rennison, J.H.; McElfresh, T.A.; Okere, I.C.; Patel, H.V.; Foster, A.B.; Patel, K.K.; Stoll, M.S.; Minkler, P.E.; Fujioka, H.; Hoit, B.D.; Young, M.E.; Hoppel, C.L.; Chandler, M.P.
Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure
Cardiovasc. Res.
79
331-340
2008
Rattus norvegicus
Manually annotated by BRENDA team
Tran, K.; Banerjee, S.; Li, H.; Noorani, H.Z.; Mensinkai, S.; Dooley, K.
Clinical efficacy and cost-effectiveness of newborn screening for medium chain acyl-CoA dehydrogenase deficiency using tandem mass spectrometry
Clin. Biochem.
40
235-241
2007
Homo sapiens
Manually annotated by BRENDA team
Ho, S.; Lukacs, Z.; Hoffmann, G.F.; Lindner, M.; Wetter, T.
Feature construction can improve diagnostic criteria for high-dimensional metabolic data in newborn screening for medium-chain acyl-CoA dehydrogenase deficiency
Clin. Chem.
53
1330-1337
2007
Homo sapiens
Manually annotated by BRENDA team
Herrema, H.; Derks, T.G.; van Dijk, T.H.; Bloks, V.W.; Gerding, A.; Havinga, R.; Tietge, U.J.; Mueller, M.; Smit, G.P.; Kuipers, F.; Reijngoud, D.J.
Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice
Hepatology
47
1894-1904
2008
Mus musculus
Manually annotated by BRENDA team
Derks, T.G.; Boer, T.S.; van Assen, A.; Bos, T.; Ruiter, J.; Waterham, H.R.; Niezen-Koning, K.E.; Wanders, R.J.; Rondeel, J.M.; Loeber, J.G.; Ten Kate, L.P.; Smit, G.P.; Reijngoud, D.J.
Neonatal screening for medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in the Netherlands: the importance of enzyme analysis to ascertain true MCAD deficiency
J. Inherit. Metab. Dis.
31
88-96
2008
Homo sapiens
Manually annotated by BRENDA team
Cyriac, J.; Venkatesh, V.; Gupta, C.
A fatal neonatal presentation of medium-chain acyl coenzyme a dehydrogenase deficiency
J. Int. Med. Res.
36
609-610
2008
Homo sapiens
Manually annotated by BRENDA team
Wilcken, B.; Haas, M.; Joy, P.; Wiley, V.; Chaplin, M.; Black, C.; Fletcher, J.; McGill, J.; Boneh, A.
Outcome of neonatal screening for medium-chain acyl-CoA dehydrogenase deficiency in Australia: a cohort study
Lancet
369
37-42
2007
Homo sapiens
Manually annotated by BRENDA team
Westermann, C.M.; de Sain-van der Velden, M.G.; van der Kolk, J.H.; Berger, R.; Wijnberg, I.D.; Koeman, J.P.; Wanders, R.J.; Lenstra, J.A.; Testerink, N.; Vaandrager, A.B.; Vianey-Saban, C.; Acquaviva-Bourdain, C.; Dorland, L.
Equine biochemical multiple acyl-CoA dehydrogenase deficiency (MADD) as a cause of rhabdomyolysis
Mol. Genet. Metab.
91
362-369
2007
Equus caballus
Manually annotated by BRENDA team
Westermann, C.M.; Dorland, L.; Votion, D.M.; de Sain-van der Velden, M.G.; Wijnberg, I.D.; Wanders, R.J.; Spliet, W.G.; Testerink, N.; Berger, R.; Ruiter, J.P.; van der Kolk, J.H.
Acquired multiple acyl-CoA dehydrogenase deficiency in 10 horses with atypical myopathy
Neuromuscul. Disord.
18
355-364
2008
Equus caballus
Manually annotated by BRENDA team
Hsu, H.W.; Zytkovicz, T.H.; Comeau, A.M.; Strauss, A.W.; Marsden, D.; Shih, V.E.; Grady, G.F.; Eaton, R.B.
Spectrum of medium-chain acyl-CoA dehydrogenase deficiency detected by newborn screening
Pediatrics
121
e1108-e1114
2008
Homo sapiens
Manually annotated by BRENDA team
Yokoi, K.; Ito, T.; Maeda, Y.; Nakajima, Y.; Ueta, A.; Nomura, T.; Koyama, N.; Kato, I.; Suzuki, S.; Kurono, Y.; Sugiyama, N.; Togari, H.
Acylcarnitine profiles during carnitine loading and fasting tests in a Japanese patient with medium-chain acyl-CoA dehydrogenase deficiency
Tohoku J. Exp. Med.
213
351-359
2007
Homo sapiens
Manually annotated by BRENDA team
Schuck, P.F.; Ferreira, G.d.a..C.; Tonin, A.M.; Viegas, C.M.; Busanello, E.N.; Moura, A.P.; Zanatta, A.; Klamt, F.; Wajner, M.
Evidence that the major metabolites accumulating in medium-chain acyl-CoA dehydrogenase deficiency disturb mitochondrial energy homeostasis in rat brain
Brain Res.
1296
117-126
2009
Rattus norvegicus
Manually annotated by BRENDA team
Horn, M.P.; Maeder-Heinemann, G.; Andrey, G.; Largiader, C.R.
Mutation screening of the medium-chain acyl-CoA dehydrogenase (MCAD) and the ornithine transcarbamylase (OTC) genes by multiplex PCR amplification and sequencing
Clin. Chem. Lab. Med.
47
56-59
2009
Homo sapiens
Manually annotated by BRENDA team
Ferreira, A.C.; Orlandi, M.P.; Oliveira, V.C.; Malta, F.S.; Caxito, F.A.; Gomes, K.B.; Valadares, E.R.; Godard, A.L.
A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil
Genet. Mol. Res.
8
487-493
2009
Homo sapiens
Manually annotated by BRENDA team
Nishina, Y.; Sato, K.; Tamaoki, H.; Setoyama, C.; Miura, R.; Shiga, K.
FT-IR spectroscopic studies on the molecular mechanism for substrate specificity/activation of medium-chain Acyl-CoA dehydrogenase
J. Biochem.
146
351-357
2009
Sus scrofa
Manually annotated by BRENDA team
Purevsuren, J.; Kobayashi, H.; Hasegawa, Y.; Mushimoto, Y.; Li, H.; Fukuda, S.; Shigematsu, Y.; Fukao, T.; Yamaguchi, S.
A novel molecular aspect of Japanese patients with medium-chain acyl-CoA dehydrogenase deficiency (MCADD): c.449-452delCTGA is a common mutation in Japanese patients with MCADD
Mol. Genet. Metab.
96
77-79
2009
Homo sapiens
Manually annotated by BRENDA team
Goetzman, E.S.
The regulation of acyl-CoA dehydrogenases in adipose tissue by rosiglitazone
Obesity (Silver Spring)
17
196-198
2009
Mus musculus
Manually annotated by BRENDA team
Zeng, J.; Wu, L.; Zhang, X.; Liu, Y.; Deng, G.; Li, D.
Oct-2-en-4-ynoyl-CoA as a specific inhibitor of acyl-CoA oxidase
Org. Lett.
10
4287-4290
2008
Rattus norvegicus
Manually annotated by BRENDA team
Sturm, M.; Herebian, D.; Mueller, M.; Laryea, M.D.; Spiekerkoetter, U.
Functional effects of different medium-chain acyl-CoA dehydrogenase genotypes and identification of asymptomatic variants
PLoS ONE
7
e45110
2012
Homo sapiens
Manually annotated by BRENDA team