Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
expression in Escherichia coli | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-octynoyl-CoA | - |
Homo sapiens | |
2-octynoyl-CoA | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00049 | - |
indolepropionyl-CoA | oxidase reaction | Sus scrofa | |
0.00094 | - |
decanoyl-CoA | - |
Sus scrofa | |
0.0023 | - |
octanoyl-CoA | - |
Sus scrofa | |
0.0029 | - |
decanoyl-CoA | - |
Homo sapiens | |
0.003 | - |
octanoyl-CoA | - |
Homo sapiens | |
0.0036 | - |
hexanoyl-CoA | - |
Sus scrofa | |
0.0068 | - |
hexanoyl-CoA | - |
Homo sapiens | |
0.0087 | - |
indolepropionyl-CoA | - |
Homo sapiens | |
0.0099 | - |
ferrocenium hexafluorophosphate | substrate indolepropionyl-CoA | Homo sapiens | |
0.01 | - |
indolepropionyl-CoA | - |
Sus scrofa | |
0.014 | - |
furylpropionyl-CoA | - |
Sus scrofa | |
0.0144 | - |
furylpropionyl-CoA | - |
Homo sapiens | |
0.0426 | - |
[4-(dimethylamino)phenyl]propionyl-CoA | - |
Homo sapiens | |
0.061 | - |
[4-(dimethylamino)phenyl]propionyl-CoA | - |
Sus scrofa | |
0.069 | - |
ferrocenium hexafluorophosphate | substrate octanoyl-CoA | Homo sapiens | |
0.264 | - |
butanoyl-CoA | - |
Sus scrofa | |
0.45 | - |
butanoyl-CoA | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
43000 | - |
4 * 43000, recombinant enzyme, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant liver enzyme, DEAE-Sephacel, hydroxyapatite, tandem column-chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
4.46 | - |
substrate indolepropionyl-CoA, ferrocenium hexafluorophosphate as electron carrier | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
butanoyl-CoA + acceptor | - |
Homo sapiens | crotonyl-CoA + reduced acceptor | - |
? | |
butanoyl-CoA + acceptor | - |
Sus scrofa | crotonyl-CoA + reduced acceptor | - |
? | |
decanoyl-CoA + ferricenium hexafluorophosphate | - |
Sus scrofa | 2-decenoyl-CoA + ferrocenium hexafluorophosphate | - |
r | |
decanoyl-CoA + ferrocenium hexafluorophosphate | - |
Sus scrofa | trans-dec-2-enoyl-CoA + reduced ferrocenium hexafluorophosphate | - |
r | |
furylpropionyl-CoA + ferricenium hexafluorophosphate | - |
Homo sapiens | furylacryloyl-CoA + ferrocenium hexafluorophosphate | - |
? | |
furylpropionyl-CoA + ferricenium hexafluorophosphate | - |
Sus scrofa | furylacryloyl-CoA + ferrocenium hexafluorophosphate | - |
? | |
hexanoyl-CoA + ferricenium hexafluorophosphate | - |
Sus scrofa | trans-hex-2-enoyl-CoA + ferrocenium hexafluorophosphate | - |
r | |
hexanoyl-CoA + ferrocenium hexafluorophosphate | - |
Sus scrofa | trans-hex-2-enoyl-CoA + reduced ferrocenium hexafluorophosphate | - |
r | |
indolepropionyl-CoA + ferricenium hexafluorophosphate | - |
Homo sapiens | indoleacryloyl-CoA + ferrocenium hexafluorophosphate | - |
? | |
indolepropionyl-CoA + ferricenium hexafluorophosphate | - |
Sus scrofa | indoleacryloyl-CoA + ferrocenium hexafluorophosphate | - |
? | |
indolepropionyl-CoA + O2 | very low activity | Homo sapiens | indoleacryloyl-CoA + H2O2 | - |
? | |
indolepropionyl-CoA + O2 | very low activity | Sus scrofa | indoleacryloyl-CoA + H2O2 | - |
? | |
[4-(dimethylamino)phenyl]propionyl-CoA + ferricenium hexafluorophosphate | - |
Homo sapiens | 4-(dimethylamino)cinnamoyl-CoA + ferrocenium hexafluorophosphate | - |
? | |
[4-(dimethylamino)phenyl]propionyl-CoA + ferricenium hexafluorophosphate | - |
Sus scrofa | 4-(dimethylamino)cinnamoyl-CoA + ferrocenium hexafluorophosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | - |
Sus scrofa |
tetramer | 4 * 43000, recombinant enzyme, SDS-PAGE | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.016 | - |
indolepropionyl-CoA | oxidase reaction | Sus scrofa | |
0.46 | - |
indolepropionyl-CoA | - |
Sus scrofa | |
0.61 | - |
[4-(dimethylamino)phenyl]propionyl-CoA | - |
Sus scrofa | |
3.4 | - |
indolepropionyl-CoA | - |
Homo sapiens | |
4.6 | - |
[4-(dimethylamino)phenyl]propionyl-CoA | - |
Homo sapiens | |
6.2 | - |
butanoyl-CoA | - |
Sus scrofa | |
7.4 | - |
decanoyl-CoA | - |
Homo sapiens | |
8.6 | - |
decanoyl-CoA | - |
Sus scrofa | |
11.5 | - |
butanoyl-CoA | - |
Homo sapiens | |
13.2 | - |
furylpropionyl-CoA | - |
Sus scrofa | |
13.6 | - |
furylpropionyl-CoA | - |
Homo sapiens | |
14.2 | - |
hexanoyl-CoA | - |
Homo sapiens | |
19.2 | - |
octanoyl-CoA | - |
Homo sapiens | |
19.6 | - |
octanoyl-CoA | - |
Sus scrofa | |
20.6 | - |
hexanoyl-CoA | - |
Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00036 | - |
2-octynoyl-CoA | competitive vs. indolepropionyl-CoA | Homo sapiens |