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(4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-docosahexaenoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
(5Z,8Z,11Z,14Z,17Z) -5,8,11,14,17-icosapentaenoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
2,6-dimethylheptanoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
4,8,12-trimethyltridecanoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
4-cis,7-cis-decadienoyl-CoA + Meldola's Blue + iodonitrotetrazoliumchloride
2-trans,4-cis,7cis-decatrienoyl-CoA + reduced acceptor
-
cis-double bond has almost no effect on velocity of general acyl-CoA dehydrogenase
-
?
4-cis-decenoyl-CoA + Meldola's Blue + iodonitrotetrazoliumchloride
2-trans,4-cis-decadienoyl-CoA + reduced acceptor
-
cis-double bond has almost no effect on velocity of general acyl-CoA dehydrogenase
-
?
4-decynoyl-CoA + Meldola's Blue + iodonitrotetrazoliumchloride
trans-2-ene-4-decynoyl-CoA + reduced acceptor
-
cis-double bond has almost no effect on velocity of general acyl-CoA dehydrogenase
-
?
4-oxaoctanoyl-CoA + phenazine methosulfate + 2,6-dichlorophenolindophenol
4-thia-trans-2-octenoyl-CoA + reduced 2,6-dichlorophenolindophenol
-
poor substrate, oxidized at about 10% of the rate of octanoyl-CoA
-
?
4-thiaoctanoyl-CoA + phenazine methosulfate + 2,6-dichlorophenolindophenol
4-thia-trans-2-octenoyl-CoA + reduced 2,6-dichlorophenolindophenol
-
oxidized 1.5fold faster than octanoyl-CoA
-
?
5-cis-decenoyl-CoA + Meldola's Blue + iodonitrotetrazoliumchloride
2-trans,5-cis-decadienoyl-CoA + reduced acceptor
-
cis-double bond has almost no effect on velocity of general acyl-CoA dehydrogenase
-
?
6-cis-decenoyl-CoA + Meldola's Blue + iodonitrotetrazoliumchloride
2-trans,6-cis-decadienoyl-CoA + reduced acceptor
-
cis-double bond has almost no effect on velocity of general acyl-CoA dehydrogenase
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
acyl-CoA + electron transfer flavoprotein
2,3-dehydroacyl-CoA + reduced electron transfer flavoprotein
all-cis-4,7,10,13-hexadecatetraenoyl-CoA + Meldola's Blue + iodonitrotetrazoliumchloride
2-trans-all-cis-4,7,10,13-hexadecapentaenoyl-CoA + reduced acceptor
-
cis-double bond has almost no effect on velocity of general acyl-CoA dehydrogenase
-
?
arachidonoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
arachidoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
beta-(2-furyl)propionyl-CoA + electron transfer flavoprotein + 2,6-dichloroindophenol
trans-beta-(2-furyl)acryloyl-CoA + reduced acceptor
beta-(2-furyl)propionyl-CoA + O2
trans-beta-(2-furyl)acryloyl-CoA + H2O2
-
slow oxidase activity
-
?
beta-(2-furyl)propionyl-CoA + pyocyanine
trans-beta-(2-furyl)acryloyl-CoA + reduced pyocanine
-
-
-
?
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
butanoyl-CoA + electron-transfer flavoprotein
crotonoyl-CoA + reduced electron-transfer flavoprotein
-
-
-
-
r
crotonyl-CoA + H2O
L-3-hydroxy-butyryl-CoA
-
enoyl-CoA hydratase activity
-
?
decanoyl-CoA + 2,6-dichlorophenolindophenol
2-decenoyl-CoA + reduced 2,6-dichorophenolindophenol
-
-
-
-
r
decanoyl-CoA + acceptor
2-decenoyl-CoA + reduced acceptor
decanoyl-CoA + electron transfer flavoprotein
(2E)-2-decenoyl-CoA + reduced electron transfer flavoprotein
-
-
-
-
?
decanoyl-CoA + electron transfer flavoprotein
decenoyl-CoA + reduced electron transfer flavoprotein
decanoyl-CoA + ferricenium hexafluorophosphate
2-decenoyl-CoA + ferrocenium hexafluorophosphate
-
-
-
-
r
decanoyl-CoA + ferrocenium hexafluorophosphate
trans-dec-2-enoyl-CoA + reduced ferrocenium hexafluorophosphate
-
-
-
-
r
decanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
2-trans-decenoyl-CoA + reduced acceptor
docosanoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
dodecanoyl-CoA + acceptor
2-dodecenoyl-CoA + reduced acceptor
dodecanoyl-CoA + electron transfer flavoprotein
dodecenoyl-CoA + reduced electron transfer flavoprotein
dodecanoyl-CoA + electron-transfer flavoprotein
+ trans-dodec-2-enoyl-CoA reduced electron-transfer flavoprotein
-
-
-
-
r
dodecanoyl-CoA + tetrazolium salt
trans-dodec-2-enoyl-CoA + reduced tetrazolium salt
-
-
-
-
r
elaidoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
furylpropionyl-CoA + ferricenium hexafluorophosphate
furylacryloyl-CoA + ferrocenium hexafluorophosphate
heptadecan-2-onyl-dethio-CoA + phenazine methosulfate + 2,6-dichloroindophenol
?
heptadecanoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
hexadecanoyl-CoA + acceptor
2-hexadecenoyl-CoA + reduced acceptor
hexadecanoyl-CoA + Meldola's Blue + iodonitrotetrazoliumchloride
2-trans-hexadecenoyl-CoA + reduced acceptor
hexanoyl-CoA + 2,6-dichloroindophenol
2-hexenoyl-CoA + reduced 2,6-dichloroindophenol
-
-
-
-
?
hexanoyl-CoA + 2,6-dichlorophenolindophenol
trans-hex-2-enoyl-CoA + reduced 2,6-dichlorophenolindophenol
-
-
-
-
r
hexanoyl-CoA + acceptor
2-hexenoyl-CoA + reduced acceptor
hexanoyl-CoA + electron transfer flavoprotein
(2E)-2-hexenoyl-CoA + reduced electron transfer flavoprotein
-
-
-
-
?
hexanoyl-CoA + ferricenium
trans-hex-2-enoyl-CoA + ferrocenium
-
-
-
-
r
hexanoyl-CoA + ferricenium hexafluorophosphate
trans-hex-2-enoyl-CoA + ferrocenium hexafluorophosphate
-
-
-
-
r
hexanoyl-CoA + ferrocenium hexafluorophosphate
trans-hex-2-enoyl-CoA + reduced ferrocenium hexafluorophosphate
-
-
-
-
r
hexanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
2-trans-hexenoyl-CoA + reduced acceptor
-
-
-
?
hexanoyl-CoA + tetrazolium salt
trans-hex-2-enoyl-CoA + reduced tetrazolium salt
-
-
-
-
r
indolepropionyl-CoA + ferricenium hexafluorophosphate
indoleacryloyl-CoA + ferrocenium hexafluorophosphate
indolepropionyl-CoA + O2
indoleacryloyl-CoA + H2O2
lauroyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
lauroyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
2-trans-dodecenoyl-CoA + reduced acceptor
-
-
-
?
linoleoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
myristoleoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
myristoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
n-octanoyl-CoA + acceptor
2-octenoyl-CoA + reduced acceptor
-
-
-
-
?
n-octanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
2-octenoyl-CoA + reduced acceptor
n-tetradecanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
2-tetradecenoyl-CoA + reduced acceptor
nonanoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
octadecanoyl-CoA + acceptor
2-octadecenoyl-CoA + reduced acceptor
octanoyl 3'-dephospho-CoA + 2,6-dichloroindophenol
?
-
-
-
-
?
octanoyl pantetheine + 2,6-dichloroindophenol
?
-
-
-
-
?
octanoyl-1,N6-etheno-CoA + 2,6-dichloroindophenol
?
-
-
-
-
?
octanoyl-CoA + 2,6-dichloroindophenol
2-octenoyl-CoA + reduced 2,6-dichloroindophenol
-
optimal substrate for wild type enzyme
-
-
?
octanoyl-CoA + acceptor
2-octenoyl-CoA + reduced acceptor
octanoyl-CoA + electron transferring flavoprotein
2-octenoyl-CoA + reduced electron transferring flavoprotein
octanoyl-CoA + ferricenium
2-octenoyl-CoA + reduced acceptor
octanoyl-CoA + ferricenium hexafluorophosphate
2-octenoyl-CoA + ferrocenium hexafluorophosphate
-
medium chain acyl-CoA dehydrogenase from kidney
-
?
octanoyl-CoA + ferriocenium hexfluorophosphate
2-octenoyl-CoA + reduced acceptor
-
-
-
-
?
octanoyl-CoA + meldola's blue
trans-oct-2-enoyl-CoA + reduced meldola's blue
-
-
-
-
r
octanoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
octanoyl-CoA + phenazine ethosulfate
trans-oct-2-enoyl-CoA + reduced phenazine ethosulfate
-
-
-
-
r
octanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
2-octenoyl-CoA + reduced acceptor
-
-
-
-
?
octanoyl-CoA + recombinant beta-Y16L electron transferring flavoprotein
trans-oct-2-enoyl-CoA + reduced recombinant beta-Y16L electron transferring flavoprotein
-
-
-
-
r
octanoyl-CoA + recombinant electron transferring flavoprotein
trans-oct-2-enoyl-CoA + reduced recombinant electron transferring flavoprotein
-
-
-
-
r
oleoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
palmitoleoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
palmitoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
pentadecanoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
pentanoyl-CoA + acceptor
2-pentenoyl-CoA + reduced acceptor
phenylpropionyl-CoA + acceptor
? + reduced acceptor
phenylpropionyl-CoA + ferricenium hexafluorophosphate
? + reduced ferricenium hexafluorophosphate
-
-
-
-
?
stearoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
tetradecanoyl-CoA + acceptor
2-tetradecenoyl-CoA + reduced acceptor
tetradecanoyl-CoA + electron transfer flavoprotein
tetradecenoyl-CoA + reduced electron transfer flavoprotein
tetradecanoyl-CoA + tetrazolium salt
tetradecenoyl-CoA + reduced tetrazolium salt
-
-
-
-
r
tetradecenoyl-CoA + reduced electron transfer flavoprotein
tetradecanoyl-CoA + electron transfer flavoprotein
-
-
-
-
r
undecanoyl-CoA + oxidized electron transfer flavoprotein
? + reduced electron transfer flavoprotein
-
-
-
-
?
[4-(dimethylamino)phenyl]propionyl-CoA + ferricenium hexafluorophosphate
4-(dimethylamino)cinnamoyl-CoA + ferrocenium hexafluorophosphate
additional information
?
-
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
2-p-iodophenyl-3-p-nitrophenyl-5-phenyl-2H-tetrazolium chloride as final electron acceptor
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
-
-
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
chain-length specificity depending on electron acceptor: with phenazine methosulfate hexanoyl-CoA, with electron transfer flavoprotein, octanoyl-CoA
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
intermediary electron acceptor: 2,6-dichloroindophenol
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
final electron acceptor: 8-dimethylamino-2,3-benzophenoxazinium chloride, trivial name meldola's blue
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
specific for chain lengths C6-C8
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
-
-
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
-
-
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
specific for chain lengths C4-C13
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
specific for chain lengths C6-C12
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
enzyme-substrate interactions
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
intermediary electron acceptor: 2,6-dichloroindophenol
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
intermediary electron acceptor: 2,6-dichloroindophenol
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
intermediary electron acceptor: 2,6-dichloroindophenol
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate or electron transfer flavoprotein
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
final electron acceptor: 8-dimethylamino-2,3-benzophenoxazinium chloride, trivial name meldola's blue
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
final electron acceptor: 8-dimethylamino-2,3-benzophenoxazinium chloride, trivial name meldola's blue
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
final electron acceptor: 8-dimethylamino-2,3-benzophenoxazinium chloride, trivial name meldola's blue
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
enzyme-substrate interactions
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
intermediary electron acceptor: 2,6-dichloroindophenol
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
intermediary electron acceptor: 2,6-dichloroindophenol
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
intermediary electron acceptor: 2,6-dichloroindophenol
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
intermediary electron acceptor: 2,6-dichloroindophenol
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate or electron transfer flavoprotein
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate or electron transfer flavoprotein
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate or electron transfer flavoprotein
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
electron acceptor: phenazine methosulfate or electron transfer flavoprotein
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
final electron acceptor: 8-dimethylamino-2,3-benzophenoxazinium chloride, trivial name meldola's blue
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
final electron acceptor: 8-dimethylamino-2,3-benzophenoxazinium chloride, trivial name meldola's blue
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
final electron acceptor: 8-dimethylamino-2,3-benzophenoxazinium chloride, trivial name meldola's blue
-
?
acyl-CoA + acceptor
2,3-dehydroacyl-CoA + reduced acceptor
-
final electron acceptor: 8-dimethylamino-2,3-benzophenoxazinium chloride, trivial name meldola's blue
-
?
acyl-CoA + electron transfer flavoprotein
2,3-dehydroacyl-CoA + reduced electron transfer flavoprotein
-
first step in beta-oxidation of fatty acids
-
?
acyl-CoA + electron transfer flavoprotein
2,3-dehydroacyl-CoA + reduced electron transfer flavoprotein
-
first step in beta-oxidation of fatty acids
-
?
beta-(2-furyl)propionyl-CoA + electron transfer flavoprotein + 2,6-dichloroindophenol
trans-beta-(2-furyl)acryloyl-CoA + reduced acceptor
-
-
-
?
beta-(2-furyl)propionyl-CoA + electron transfer flavoprotein + 2,6-dichloroindophenol
trans-beta-(2-furyl)acryloyl-CoA + reduced acceptor
-
-
-
?
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
-
-
-
-
?
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
-
-
-
?
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
-
-
-
?
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
-
-
-
-
?
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
-
-
-
-
?
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
-
-
-
?
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
-
-
-
-
?
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
-
-
-
r
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
-
reduction potential
-
?
butanoyl-CoA + acceptor
crotonyl-CoA + reduced acceptor
-
potentiometric measurements
-
?
decanoyl-CoA + acceptor
2-decenoyl-CoA + reduced acceptor
-
-
-
?
decanoyl-CoA + acceptor
2-decenoyl-CoA + reduced acceptor
-
acceptors: phenazine methosulfate or electron transferring flavoprotein
-
?
decanoyl-CoA + acceptor
2-decenoyl-CoA + reduced acceptor
-
-
-
?
decanoyl-CoA + acceptor
2-decenoyl-CoA + reduced acceptor
-
72% of activity with hexanoyl-CoA
-
?
decanoyl-CoA + electron transfer flavoprotein
decenoyl-CoA + reduced electron transfer flavoprotein
-
-
-
?
decanoyl-CoA + electron transfer flavoprotein
decenoyl-CoA + reduced electron transfer flavoprotein
-
-
-
?
decanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
2-trans-decenoyl-CoA + reduced acceptor
-
-
-
-
?
decanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
2-trans-decenoyl-CoA + reduced acceptor
-
electron acceptor: Meldola's Blue and iodonitrotetrazoliumchloride, general and long-chain acyl-CoA dehydrogenase
-
?
decanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
2-trans-decenoyl-CoA + reduced acceptor
-
-
-
-
?
dodecanoyl-CoA + acceptor
1.3.8.7 medium-chain acyl-CoA dehydrogenase
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