220.127.116.110: NADP-retinol dehydrogenase
This is an abbreviated version!
For detailed information about NADP-retinol dehydrogenase, go to the full flat file. Reaction
NADP + +
NADPH H+ Synonyms
aldehyde dehydrogenase, ALDH, all-trans retinal reductase, all-trans-retinol dehydrogenase, CG2065, CG2070, CG30491, CG3842, DHRS3, hRDH5, hRoDH, More, mouse RDH11, mRDH11, NADP(H)-dependent retinol dehydrogenase/reductase, NADP+-dependent all-trans-retinol dehydrogenase, NDRD, NRDR, NRDRA1, NRDRB1, NRDRB2, peroxisomal NADP(H)-dependent retinol dehydrogenase-reductase, photoreceptor retinol dehydrogenase, photoreceptor-associated retinol dehydrogenase, photoreceptor-specific retinol dehydrogenase, prRDH, RalR1, RDH, RDH10, RDH11, RDH12, RDH13, RDH14, RDH8, retinal reductase, retinal reductase 1, retinaldehyde reductase, retinoid dehydrogenase/reductase, Retinol dehydrogenase, retinol dehydrogenase 10, retinol dehydrogenase 11, retinol dehydrogenase 12, retinol dehydrogenase 13, retinol dehydrogenase 8, retinol dehydrogenase [NADP+], retinol dehydrogenase-10, retSDR1, RHD8, short-chain dehydrogenase/reductase RRD
Organism on EC 18.104.22.1680 - NADP-retinol dehydrogenase
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gene harbours two initiation sites, one of which encodes a 279 and the other a 260 amino acids protein
; isoform 4, from full length cDNA, isoform of NRDR without residues 85-118; alternatively spliced variant NRDRB1 with a complete deletion of exon 3, activity of NRDRB1 much lower than activity of NRDR in forward and reverse reaction; isoform 5, from full length cDNA, isoform of NRDR without residues 85-118 and 160-204; alternatively spliced variant NRDRB2 with a complete deletion of exons 3 and 6; isoform 6, from full length cDNA, isoform of NRDR without residues 1-203; alternatively spliced variant NRDRA1 with a complete deletion of exons 3-6
; recombinant enzyme
Austrian kindreds with individuals affected by autosomal recessive childhood-onset severe retinal dystrophy
isoforms RDH12 and RDH13
isoforms Rdh11, Rdh12
mouse monoclonal anti-GRK1 (G-proteinassociated rhodopsin kinase-1)