Reference on EC 2.7.7.8 - polyribonucleotide nucleotidyltransferase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Zhou, Z.; Deutscher, M.P.
An essential function for the phosphate-dependent exoribonucleases RNase PH and polynucleotide phosphorylase
J. Bacteriol.
179
4391-4395
1997
Escherichia coli
Bauer, P.I.; Buki, K.G.
The purification of polynucleotide phosphorylase from Thermus aquaticus by the use of heparin-sepharose 4B affinity chromatography
Acta Biochim. Biophys. Acad. Sci. Hung.
16
135-144
1981
Thermus aquaticus
Littauer, U.Z.; Soreq, H.
Polynucleotide phosphorylase
The Enzymes, 3rd. Ed. (Boyer, P. D. , ed. )
15B
517-553
1982
Azotobacter vinelandii, Achromobacter sp., Synechococcus elongatus PCC 7942 = FACHB-805, Geobacillus stearothermophilus, Bacillus amyloliquefaciens, Brevibacterium sp., Cavia porcellus, Clostridium perfringens, Escherichia coli, Enterococcus faecalis, Halobacterium salinarum, Micrococcus luteus, Nicotiana tabacum, Rattus norvegicus, Sinorhizobium meliloti, Rhodospirillum rubrum, Streptococcus pyogenes, Thermus aquaticus, Bacillus amyloliquefaciens BaM-2, Achromobacter sp. KR. 170-4
-
Godefroy-Colburn, T.; Grunenberg-Manago, M.
Polynucleotide phosphorylase
The Enzymes, 3rd. Ed. (Boyer, P. D. , ed. )
7
533-574
1972
Ascaris lumbricoides, Auxenochlorella pyrenoidosa, Cavia porcellus, Escherichia coli, Halobacterium salinarum, Homo sapiens, Lactiplantibacillus plantarum, Micrococcus luteus, Neisseria meningitidis, Pseudomonas aeruginosa, Rattus norvegicus, Salmonella enterica subsp. enterica serovar Typhimurium, Spinacia oleracea, Synechococcus elongatus PCC 7942 = FACHB-805, Triticum aestivum
-
Soreq, H.; Littauer, U.Z.
Purification and characterization of polynucleotide phosphorylase from Escherichia coli. Probe for the analysis of 3 sequences of RNA
J. Biol. Chem.
252
6885-6888
1977
Escherichia coli
Hishinuma, F.; Hirai, K.; Sakaguchi, K.
Thermophilic polynucleotide phosphorylase from Thermus thermophilus. Purification and properties of an altered form of enzyme which lacks phosphorolytic activity to polynucleotide
Eur. J. Biochem.
77
575-583
1977
Thermus thermophilus
Ochoa, S.; Mii, S.
Enzymatic synthesis of polynucleotides. IV. Purification and properties of polynucleotide phosphorylase of Azobacter vinelandii
J. Biol. Chem.
236
3303-3311
1961
Azotobacter vinelandii
Nolden, W.T.; Richter, G.
polynucleotide phosphorylase from a cyanobacterium (Synechococcus sp.): subunit composition and properties
Z. Naturforsch. C
37c
600-608
1982
Synechococcus sp.
-
Soe, G.; Yamashita, J.
Purification and properties of polynucleotide phosphorylase from photosynthetic bacterium Rhodospirillum rubrum
J. Biochem.
87
101-110
1980
Rhodospirillum rubrum
Hunt, R.E.; Cowles, J.R.
Physiological levels and properties of polynucleotide phosphorylase of Rhizobium meliloti
J. Gen. Microbiol.
102
403-411
1977
Bradyrhizobium japonicum, Sinorhizobium meliloti, Sinorhizobium meliloti F-28
-
Harry, K.; Sharma, N.; Fitt, P.S.
Preparation and properties of highly-purified Vibrio costicola polynucleotide phosphorylase
Biochim. Biophys. Acta
828
29-38
1985
Salinivibrio costicola
Khan, Z.A.; Fraenkel-Conrat, H.
Purification and characterization of polynucleotide phosphorylase from cucumber
Proc. Natl. Acad. Sci. USA
82
1311-1315
1985
Cucumis sativus
Yang, H.H.; Thayer, D.W.; Yang, S.P.
Purification of an Endogenous polynucleotide phosphorylase from Brevibacterium JM98A
Appl. Environ. Microbiol.
38
159-161
1979
Brevibacterium sp., Brevibacterium sp. JM 98A
Smith, J.C.; Eaton, M.A.W.
Purification of polynucleotide phosphorylase by affinity chromatography and some properties of the purified enzymes
Nucleic Acids Res.
1
1763-1773
1974
Geobacillus stearothermophilus, Escherichia coli
Letendre, C.H.; Singer, M.F.
Further characterization of the polynucleotide phosphorylase of Micrococcus luteus
Nucleic Acids Res.
2
149-163
1975
Micrococcus luteus
See, Y.P.; Fitt, P.S.
A study of the localization of polynucleotide phosphorylase within rat liver cells and of its distribution among rat tissues and diverse animal species
Biochem. J.
130
355-362
1972
Bos taurus, Carassius auratus, Cavia porcellus, Gallus gallus, Oryctolagus cuniculus, Rattus norvegicus
Brishammar, S.; Juntti, N.
RNA-synthesizing enzymes in healthy and TMV-infected tobacco leaves. Partial purification and characterization to tobacco polynucleotide phosphorylase
Arch. Biochem. Biophys.
164
224-232
1974
Nicotiana tabacum
See, Y.P.; Fitt, P.S.
Partial purification and properties of rat liver mitochondrial polynucleotide phosphorylase
Biochem. J.
130
343-353
1972
Rattus norvegicus
Barbehenn, E.K.; Craine, J.E.; Chrambach, A.; Klee, C.B.
Characterization of polynucleotide phosphorylase from Micrococcus luteus and isolation of the 13,000 base poly(A) product of the polymerization reaction
J. Biol. Chem.
257
1007-1016
1982
Micrococcus luteus
Waters, M.F.; McLennan, A.G.; Carr, N.G.
Purification and activity gel analysis of polynucleotide phosphorylase from the cyanobacterium Nostoc sp. MAC
J. Gen. Microbiol.
135
2045-2054
1989
Nostoc sp., Nostoc sp. MAC
-
Erickson, R.J.; Grosch, J.C.
Isolation and characterization of a polynucleotide phosphorylase from Bacillus amyloliquefaciens
J. Bacteriol.
130
869-876
1977
Bacillus amyloliquefaciens
Simuth, J.; Zelinka, J.S.; Polek, B.
Polynucleotide phosphorylase from Streptomyces aureofaciens: purification and properties
Biochim. Biophys. Acta
379
397-407
1975
Kitasatospora aureofaciens
Chou, J.Y.; Singer, M.F.
Deoxyadenosine diphosphate as a substrate and inhibitor of polynucleotide phosphorylase of Micrococcus luteus. I. Deoxyadenosine diphosphate as a substrate for polymerization and the exchange reaction with inorganic 32 P
J. Biol. Chem.
246
7486-7496
1971
Micrococcus luteus
Chou, J.Y.; Singer, M.F.
Deoxyadenosine diphosphate as a substrate and inhibitor of polynucleotide phosphorylase of Micrococcus luteus. II. Inhibition of the initiation of adenosine diphosphate polymerization by deoxyadenosine diphosphate
J. Biol. Chem.
246
7497-7504
1971
Micrococcus luteus
Chou, J.Y.; Singer, M.F.
Deoxyadenosine diphosphate as a substrate and inhibitor of polynucleotide phosphorylase of Micrococcus luteus. 3. Copolymerization of adenosine diphosphate and deoxyadenosine diphosphate
J. Biol. Chem.
246
7505-7513
1971
Micrococcus luteus
Carpousis, A.J.; Van Houwe, G.; Ehretsmann, C.; Krisch, H.M.
Copurification of E. coli RNase E and PNPase: evidence for a specific association between two enzymes important in RNA processing and degradation
Cell
76
889-900
1994
Escherichia coli
Mitra, S.; Hue, K.; Bechhofer, D.H.
In vitro processing activity of Bacillus subtilis polynucleotide phosphorylase
Mol. Microbiol.
19
329-342
1996
Bacillus subtilis
Lisitsky, I.; Schuster, G.
Preferential degradation of polyadenylated and polyuridinylated RNAs by the bacterial exoribonuclease polynucleotide phosphorylase
Eur. J. Biochem.
261
468-474
1999
Escherichia coli
Symmons, M.F.; Jones, G.H.; Luisi, B.F.
A duplicated fold is the structural basis for polynucleotide phosphorylase catalytic activity, processivity, and regulation
Structure Fold. Des.
8
1215-1226
2000
Streptomyces antibioticus (Q53597), Streptomyces antibioticus
Mohanty, B.K.; Kushner, S.R.
Polynucleotide phosphorylase functions both as a 3' -> 5' exonuclease and a poly(A) polymerase in Escherichia coli
Proc. Natl. Acad. Sci. USA
97
11966-11971
2000
Escherichia coli
Spickler, C.; Mackie, G.A.
Action of RNase II and polynucleotide phosphorylase against RNAs containing stem-loops of defined structure
J. Bacteriol.
182
2422-2427
2000
Escherichia coli
Zangrossi, S.; Briani, F.; Ghisotti, D.; Regonesi, M.E.; Tortora, P.; Deho, G.
Transcriptional and post-transcriptional control of polynucleotide phosphorylase during cold acclimation in Escherichia coli
Mol. Microbiol.
36
1470-1480
2000
Escherichia coli
Baginsky, S.; Shteiman-Kotler, A.; Liveanu, V.; Yehudai-Resheff, S.; Bellaoui, M.; Settlage, R.E.; Shabanowitz, J.; Hunt, D.F.; Schuster, G.; Gruissem, W.
Chloroplast PNPase exists as a homo-multimer enzyme complex that is distinct from the Escherichia coli degradosome
RNA
7
1464-1475
2001
Escherichia coli, Spinacia oleracea
Hayakawa, H.; Kuwano, M.; Sekiguchi, M.
Specific binding of 8-oxoguanine-containing RNA to polynucleotide phosphorylase protein
Biochemistry
40
9977-9982
2001
Escherichia coli
Yehudai-Resheff, S.; Hirsh, M.; Schuster, G.
Polynucleotide phosphorylase functions as both an exonuclease and a poly(A) polymerase in spinach chloroplasts
Mol. Cell. Biol.
21
5408-5416
2001
Escherichia coli, Spinacia oleracea
Walter, M.; Kilian, J.; Kudla, J.
PNPase activity determines the efficiency of mRNA 3'-end processing, the degradation of tRNA and the extent of polyadenylation in chloroplasts
EMBO J.
21
6905-6914
2002
Arabidopsis thaliana
Bermudez-Cruz, R.M.; Garcia-Mena, J.; Montanez, C.
Polynucleotide phosphorylase binds to ssRNA with same affinity as to ssDNA
Biochimie
84
321-328
2002
Escherichia coli
Mohanty, B.K.; Kushner, S.R.
Polyadenylation of Escherichia coli transcripts plays an integral role in regulating intracellular levels of polynucleotide phosphorylase and RNase E
Mol. Microbiol.
45
1315-1324
2002
Escherichia coli
Leszczyniecka, M.; Kang, D.C.; Sarkar, D.; Su, Z.Z.; Holmes, M.; Valerie, K.; Fisher, P.B.
Identification and cloning of human polynucleotide phosphorylase, hPNPase old-35, in the context of terminal differentiation and cellular senescence
Proc. Natl. Acad. Sci. USA
99
16636-16641
2002
Homo sapiens (Q8TCS8), Homo sapiens
Yehudai-Resheff, S.; Portnoy, V.; Yogev, S.; Adir, N.; Schuster, G.
Domain analysis of the chloroplast polynucleotide phosphorylase reveals discrete functions in RNA degradation, polyadenylation, and sequence homology with exosome proteins
Plant Cell
15
2003-2019
2003
Spinacia oleracea (Q41370), Spinacia oleracea
Sarkar, D.; Lebedeva, I.V.; Emdad, L.; Kang, D.C.; Baldwin, A.S.; Fisher, P.B.
Human polynucleotide phosphorylase (hPNPaseold-35): a potential link between aging and inflammation
Cancer Res.
64
7473-7478
2004
Homo sapiens
Rosenzweig, J.A.; Weltman, G.; Plano, G.V.; Schesser, K.
Modulation of Yersinia type three secretion systen by the S1 domain of polynucleotide phosphorylase
J. Biol. Chem.
280
156-163
2005
Yersinia pseudotuberculosis
Nagaike, T.; Suzuki, T.; Katoh, T.; Ueda, T.
Human mitochondrial mRNAs are stabilized with polyadenylation regulated by mitochondria-specific poly(A) polymerase and polynucleotide phosphorylase
J. Biol. Chem.
280
19721-19727
2005
Homo sapiens
Perrin, R.; Lange, H.; Grienberger, J.M.; Gagliardi, D.
AtmtPNPase is required for multiple aspects of the 18S rRNA metabolism in Arabidopsis thaliana mitochondria
Nucleic Acids Res.
32
5174-5182
2004
Arabidopsis thaliana
Hayakawa, H.; Sekiguchi, M.
Human polynucleotide phosphorylase protein in response to oxidative stress
Biochemistry
45
6749-6755
2006
Homo sapiens
Duran-Figueroa, N.V.; Pina-Escobedo, A.; Schroeder, I.; Simons, R.W.; Garcia-Mena, J.
Polynucleotide phosphorylase interacts with ribonuclease E through a betabetaalphabetabetaalpha domain
Biochimie
88
725-735
2006
Escherichia coli (P05055), Escherichia coli
Briani, F.; Del Favero, M.; Capizzuto, R.; Consonni, C.; Zangrossi, S.; Greco, C.; De Gioia, L.; Tortora, P.; Deho, G.
Genetic analysis of polynucleotide phosphorylase structure and functions
Biochimie
89
145-157
2007
Escherichia coli, Escherichia coli (P05055)
French, S.W.; Dawson, D.W.; Chen, H.; Rainey, R.N.; Sievers, S.A.; Balatoni, C.E.; Wong, L.; Troke, J.J.; Nguyen, M.T.; Koehler, C.M.; Teitell, M.A.
The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity
Cancer Lett.
248
198-210
2007
Homo sapiens (Q8TCS8)
Sarkar, D.; Park, E.S.; Fisher, P.B.
Defining the mechanism by which IFN-beta dowregulates c-myc expression in human melanoma cells: pivotal role for human polynucleotide phosphorylase (hPNPaseold-35)
Cell Death Differ.
13
1541-1553
2006
Homo sapiens
Rosenzweig, J.A.; Chromy, B.; Echeverry, A.; Yang, J.; Adkins, B.; Plano, G.V.; McCutchen-Maloney, S.; Schesser, K.
Polynucleotide phosphorylase independently controls virulence factor expression levels and export in Yersinia spp.
FEMS Microbiol. Lett.
270
255-264
2007
Yersinia sp.
Ygberg, S.E.; Clements, M.O.; Rytkoenen, A.; Thompson, A.; Holden, D.W.; Hinton, J.C.; Rhen, M.
Polynucleotide phosphorylase negatively controls spv virulence gene expression in Salmonella enterica
Infect. Immun.
74
1243-1254
2006
Salmonella enterica
Chen, H.W.; Rainey, R.N.; Balatoni, C.E.; Dawson, D.W.; Troke, J.J.; Wasiak, S.; Hong, J.S.; McBride, H.M.; Koehler, C.M.; Teitell, M.A.; French, S.W.
Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis
Mol. Cell. Biol.
26
8475-8487
2006
Homo sapiens
Marchi, P.; Longhi, V.; Zangrossi, S.; Gaetani, E.; Briani, F.; Deho, G.
Autogenous regulation of Escherichia coli polynucleotide phosphorylase during cold acclimation by transcription termination and antitermination
Mol. Genet. Genomics
278
75-84
2007
Escherichia coli
Amblar, M.; Barbas, A.; Gomez-Puertas, P.; Arraiano, C.M.
The role of the S1 domain in exoribonucleolytic activity: substrate specificity and multimerization
RNA
13
317-327
2007
Escherichia coli (P05055), Escherichia coli
Favaro, R.; Deho, G.
Polynucleotide phosphorylase-deficient mutants of Pseudomonas putida
J. Bacteriol.
185
5279-5286
2003
Pseudomonas putida (O87792), Pseudomonas putida, Pseudomonas putida KT 2240 (O87792)
Shi, Z.; Yang, W.Z.; Lin-Chao, S.; Chak, K.F.; Yuan, H.S.
Crystal structure of Escherichia coli PNPase: Central channel residues are involved in processive RNA degradation
RNA
14
2361-2371
2008
Escherichia coli (P05055), Escherichia coli
Wu, J.; Li, Z.
Human polynucleotide phosphorylase reduces oxidative RNA damage and protects HeLa cell against oxidative stress
Biochem. Biophys. Res. Commun.
372
288-292
2008
Homo sapiens
Matus-Ortega, M.E.; Regonesi, M.E.; Pina-Escobedo, A.; Tortora, P.; Deho, G.; Garcia-Mena, J.
The KH and S1 domains of Escherichia coli polynucleotide phosphorylase are necessary for autoregulation and growth at low temperature
Biochim. Biophys. Acta
1769
194-203
2007
Escherichia coli (P05055), Escherichia coli
Sarkar, D.; Park, E.S.; Barber, G.N.; Fisher, P.B.
Activation of double-stranded RNA dependent protein kinase, a new pathway by which human polynucleotide phosphorylase (hPNPase(old-35)) induces apoptosis
Cancer Res.
67
7948-7953
2007
Homo sapiens
Falaleeva, M.V.; Chetverina, H.V.; Ugarov, V.I.; Uzlova, E.A.; Chetverin, A.B.
Factors influencing RNA degradation by Thermus thermophilus polynucleotide phosphorylase
FEBS J.
275
2214-2226
2008
Thermus thermophilus (Q9ZAE1), Thermus thermophilus
Awano, N.; Inouye, M.; Phadtare, S.
RNase activity of polynucleotide phosphorylase is critical at low temperature in Escherichia coli and is complemented by RNase II
J. Bacteriol.
190
5924-5933
2008
Escherichia coli, Escherichia coli JM83
Chang, S.A.; Cozad, M.; Mackie, G.A.; Jones, G.H.
Kinetics of polynucleotide phosphorylase: comparison of enzymes from Streptomyces and Escherichia coli and effects of nucleoside diphosphates
J. Bacteriol.
190
98-106
2008
Escherichia coli, Streptomyces coelicolor
Carzaniga, T.; Briani, F.; Zangrossi, S.; Merlino, G.; Marchi, P.; Deho, G.
Autogenous regulation of Escherichia coli polynucleotide phosphorylase expression revisited
J. Bacteriol.
191
1738-1748
2009
Escherichia coli (P05055), Escherichia coli
Del Favero, M.; Mazzantini, E.; Briani, F.; Zangrossi, S.; Tortora, P.; Deho, G.
Regulation of Escherichia coli polynucleotide phosphorylase by ATP
J. Biol. Chem.
283
27355-27359
2008
Escherichia coli
Chan, I.; Lebedeva, I.V.; Su, Z.Z.; Sarkar, D.; Valerie, K.; Fisher, P.B.
Progression elevated gene-3 promoter (PEG-Prom) confers cancer cell selectivity to human polynucleotide phosphorylase (hPNPase(old-35))-mediated growth suppression
J. Cell. Physiol.
215
401-409
2008
Homo sapiens
Nurmohamed, S.; Vaidialingam, B.; Callaghan, A.J.; Luisi, B.F.
Crystal structure of Escherichia coli polynucleotide phosphorylase core bound to RNase E, RNA and manganese: Implications for catalytic mechanism and RNA degradosome assembly
J. Mol. Biol.
389
17-33
2009
Escherichia coli (A7ZS61), Escherichia coli
Portnoy, V.; Palnizky, G.; Yehudai-Resheff, S.; Glaser, F.; Schuster, G.
Analysis of the human polynucleotide phosphorylase (PNPase) reveals differences in RNA binding and response to phosphate compared to its bacterial and chloroplast counterparts
RNA
14
297-309
2008
Homo sapiens
Slomovic, S.; Schuster, G.
Stable PNPase RNAi silencing: its effect on the processing and adenylation of human mitochondrial RNA
RNA
14
310-323
2008
Homo sapiens
Andrade, J.M.; Arraiano, C.M.
PNPase is a key player in the regulation of small RNAs that control the expression of outer membrane proteins
RNA
14
543-551
2008
Escherichia coli, Escherichia coli MG1693
Haddad, N.; Burns, C.M.; Bolla, J.M.; Prevost, H.; Federighi, M.; Drider, D.; Cappelier, J.M.
Long-term survival of Campylobacter jejuni at low temperatures is dependent on polynucleotide phosphorylase activity
Appl. Environ. Microbiol.
75
7310-7318
2009
Campylobacter jejuni
Wu, J.; Jiang, Z.; Liu, M.; Gong, X.; Wu, S.; Burns, C.M.; Li, Z.
Polynucleotide phosphorylase protects Escherichia coli against oxidative stress
Biochemistry
48
2012-2020
2009
Escherichia coli K-12, Escherichia coli K-12 CA244
Palanisamy, S.K.; Fletcher, C.; Tanjung, L.; Katz, M.E.; Cheetham, B.F.
Deletion of the C-terminus of polynucleotide phosphorylase increases twitching motility, a virulence characteristic of the anaerobic bacterial pathogen Dichelobacter nodosus
FEMS Microbiol. Lett.
302
39-45
2009
Dichelobacter nodosus (A5EXU0), Dichelobacter nodosus
Wang, D.D.; Shu, Z.; Lieser, S.A.; Chen, P.L.; Lee, W.H.
Human mitochondrial SUV3 and polynucleotide phosphorylase form a 330-kDa heteropentamer to cooperatively degrade double-stranded RNA with a 3'-to-5' directionality
J. Biol. Chem.
284
20812-20821
2009
Homo sapiens
Cardenas, P.P.; Carrasco, B.; Sanchez, H.; Deikus, G.; Bechhofer, D.H.; Alonso, J.C.
Bacillus subtilis polynucleotide phosphorylase 3-to-5 DNase activity is involved in DNA repair
Nucleic Acids Res.
37
4157-4169
2009
Bacillus subtilis, Bacillus subtilis BG214
Zimmer, S.; Schein, A.; Zipor, G.; Stern, D.; Schuster, G.
Polyadenylation in Arabidopsis and Chlamydomonas organelles: The input of nucleotidyltransferases, poly(A) polymerases and polynucleotide phosphorylase
Plant J.
59
88-99
2009
Arabidopsis thaliana, Chlamydomonas reinhardtii
Marchive, C.; Yehudai-Resheff, S.; Germain, A.; Fei, Z.; Jiang, X.; Judkins, J.; Wu, H.; Fernie, A.R.; Fait, A.; Stern, D.B.
Abnormal physiological and molecular mutant phenotypes link chloroplast polynucleotide phosphorylase to the phosphorus deprivation response in Arabidopsis
Plant Physiol.
151
905-924
2009
Arabidopsis thaliana
Evangelista, G.; Falasca, P.; Ruggiero, I.; Masullo, M.; Raimo, G.
Molecular and functional characterization of polynucleotide phosphorylase from the antarctic eubacterium Pseudoalteromonas haloplanktis
Protein Pept. Lett.
16
999-1005
2009
Pseudoalteromonas haloplanktis
Carzaniga, T.; Antoniani, D.; Deho, G.; Briani, F.; Landini, P.
The RNA processing enzyme polynucleotide phosphorylase negatively controls biofilm formation by repressing poly-N-acetylglucosamine (PNAG) production in Escherichia coli C
BMC Microbiol.
12
270
2012
Escherichia coli, Escherichia coli MG1655
Haddad, N.; Tresse, O.; Rivoal, K.; Chevret, D.; Nonglaton, Q.; Burns, C.M.; Prevost, H.; Cappelier, J.M.
Polynucleotide phosphorylase has an impact on cell biology of Campylobacter jejuni
Front. Cell. Infect. Microbiol.
2
30
2012
Campylobacter jejuni
Becket, E.; Tse, L.; Yung, M.; Cosico, A.; Miller, J.H.
Polynucleotide phosphorylase plays an important role in the generation of spontaneous mutations in Escherichia coli
J. Bacteriol.
194
5613-5620
2012
Escherichia coli
Wong, A.G.; McBurney, K.L.; Thompson, K.J.; Stickney, L.M.; Mackie, G.A.
The S1 and KH domains of polynucleotide phosphorylase determine the efficiency of RNA binding and autoregulation
J. Bacteriol.
195
2021-2031
2013
Escherichia coli
Nurmohamed, S.; Vincent, H.A.; Titman, C.M.; Chandran, V.; Pears, M.R.; Du, D.; Griffin, J.L.; Callaghan, A.J.; Luisi, B.F.
Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli
J. Biol. Chem.
286
14315-14323
2011
Escherichia coli, Escherichia coli MG1655
Lin, C.L.; Wang, Y.T.; Yang, W.Z.; Hsiao, Y.Y.; Yuan, H.S.
Crystal structure of human polynucleotide phosphorylase: insights into its domain function in RNA binding and degradation
Nucleic Acids Res.
40
4146-4157
2012
Homo sapiens (G8TCS8), Homo sapiens
Das, S.K.; Bhutia, S.K.; Sokhi, U.K.; Dash, R.; Azab, B.; Sarkar, D.; Fisher, P.B.
Human polynucleotide phosphorylase (hPNPase(old-35)): an evolutionary conserved gene with an expanding repertoire of RNA degradation functions
Oncogene
30
1733-1743
2011
Homo sapiens, Mus musculus
Hardwick, S.W.; Gubbey, T.; Hug, I.; Jenal, U.; Luisi, B.F.
Crystal structure of Caulobacter crescentus polynucleotide phosphorylase reveals a mechanism of RNA substrate channelling and RNA degradosome assembly
Open biology
2
120028
2012
Caulobacter vibrioides, Caulobacter vibrioides NA1000
Germain, A.; Herlich, S.; Larom, S.; Kim, S.H.; Schuster, G.; Stern, D.B.
Mutational analysis of Arabidopsis chloroplast polynucleotide phosphorylase reveals roles for both RNase PH core domains in polyadenylation, RNA 3'-end maturation and intron degradation
Plant J.
67
381-394
2011
Arabidopsis thaliana, Arabidopsis thaliana Col-0.
Das, S.K.; Sokhi, U.K.; Bhutia, S.K.; Azab, B.; Su, Z.Z.; Sarkar, D.; Fisher, P.B.
Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells
Proc. Natl. Acad. Sci. USA
107
11948-11953
2010
Homo sapiens
De Lay, N.; Gottesman, S.
Role of polynucleotide phosphorylase in sRNA function in Escherichia coli
RNA
17
1172-1189
2011
Escherichia coli, Escherichia coli MG1193
Zhang, J.Y.; Deng, X.M.; Li, F.P.; Wang, L.; Huang, Q.Y.; Zhang, C.C.; Chen, W.L.
RNase E forms a complex with polynucleotide phosphorylase in cyanobacteria via a cyanobacterial-specific nonapeptide in the noncatalytic region
RNA
20
568-579
2014
Synechocystis sp. (P72659), Synechocystis sp., Nostoc sp. (Q8YP11), Nostoc sp. PCC 7120 (Q8YP11)
Unciuleac, M.C.; Shuman, S.
Discrimination of RNA from DNA by polynucleotide phosphorylase
Biochemistry
52
6702-6711
2013
Mycolicibacterium smegmatis (A0QVQ5), Mycolicibacterium smegmatis
Chen, R.; Weng, Y.; Zhu, F.; Jin, Y.; Liu, C.; Pan, X.; Xia, B.; Cheng, Z.; Jin, S.; Wu, W.
Polynucleotide phosphorylase regulates multiple virulence factors and the stabilities of small RNAs RsmY/Z in Pseudomonas aeruginosa
Front. Microbiol.
7
247
2016
Pseudomonas aeruginosa
Engman, J.; Negrea, A.; Sigurlasdottir, S.; Geoerg, M.; Eriksson, J.; Eriksson, O.S.; Kuwae, A.; Sjoelinder, H.; Jonsson, A.B.
Neisseria meningitidis polynucleotide phosphorylase affects aggregation, adhesion, and virulence
Infect. Immun.
84
1501-1513
2016
Neisseria meningitidis FAM18 (A1KT19), Neisseria meningitidis FAM18 DSM 15464 (A1KT19)
Carzaniga, T.; Deho, G.; Briani, F.
RNase III-independent autogenous regulation of Escherichia coli polynucleotide phosphorylase via translational repression
J. Bacteriol.
197
1931-1938
2015
Escherichia coli
Numata, S.; Nagata, M.; Mao, H.; Sekimizu, K.; Kaito, C.
CvfA protein and polynucleotide phosphorylase act in an opposing manner to regulate Staphylococcus aureus virulence
J. Biol. Chem.
289
8420-8431
2014
Staphylococcus aureus (Q7A5X7), Staphylococcus aureus
Salvo, E.; Alabi, S.; Liu, B.; Schlessinger, A.; Bechhofer, D.H.
Interaction of Bacillus subtilis polynucleotide phosphorylase and RNase Y: structural mapping and effect on mRNA turnover
J. Biol. Chem.
291
6655-6663
2016
Bacillus subtilis, Bacillus subtilis BG1
Bearson, S.M.; Bearson, B.L.; Lee, I.S.; Kich, J.D.
Polynucleotide phosphorylase (PNPase) is required for Salmonella enterica serovar Typhimurium colonization in swine
Microb. Pathog.
65
63-66
2013
Salmonella enterica subsp. enterica serovar Typhimurium
Bandyra, K.J.; Sinha, D.; Syrjanen, J.; Luisi, B.F.; De Lay, N.R.
The ribonuclease polynucleotide phosphorylase can interact with small regulatory RNAs in both protective and degradative modes
RNA
22
360-372
2016
Escherichia coli
Fan, Z.; Pan, X.; Wang, D.; Chen, R.; Fu, T.; Yang, B.; Jin, Y.; Bai, F.; Cheng, Z.; Wu, W.
Pseudomonas aeruginosa polynucleotide phosphorylase controls tolerance to aminoglycoside antibiotics by regulating the MexXY multidrug efflux pump
Antimicrob. Agents Chemother.
65
e01846
2020
Pseudomonas aeruginosa (Q9HV59), Pseudomonas aeruginosa
Yaseen, Y.; Diop, A.; Gancel, F.; Bechet, M.; Jacques, P.; Drider, D.
Polynucleotide phosphorylase is involved in the control of lipopeptide fengycin production in Bacillus subtilis
Arch. Microbiol.
200
783-791
2018
Bacillus subtilis (P50849), Bacillus subtilis, Bacillus subtilis 168 (P50849)
Raj, R.; Mitra, S.; Gopal, B.
Characterization of Staphylococcus epidermidis polynucleotide phosphorylase and its interactions with ribonucleases RNase J1 and RNase J2
Biochem. Biophys. Res. Commun.
495
2078-2084
2018
Staphylococcus epidermidis (Q8CST1), Staphylococcus epidermidis, Staphylococcus epidermidis ATCC 12228 (Q8CST1)
Carzaniga, T.; Sbarufatti, G.; Briani, F.; Deho, G.
Polynucleotide phosphorylase is implicated in homologous recombination and DNA repair in Escherichia coli
BMC Microbiol.
17
81
2017
Escherichia coli
Fan, Z.; Chen, H.; Li, M.; Pan, X.; Fu, W.; Ren, H.; Chen, R.; Bai, F.; Jin, Y.; Cheng, Z.; Jin, S.; Wu, W.
Pseudomonas aeruginosa polynucleotide phosphorylase contributes to ciprofloxacin resistance by regulating PrtR
Front. Microbiol.
10
1762
2019
Pseudomonas aeruginosa (Q9HV59), Pseudomonas aeruginosa
Malla, S.; Li, Z.
Functions of conserved domains of human polynucleotide phosphorylase on RNA oxidation
Insights Biomed. Res.
3
62-67
2019
Homo sapiens (Q8TCS8), Homo sapiens
Cameron, T.A.; De Lay, N.R.
The phosphorolytic exoribonucleases polynucleotide phosphorylase and RNase PH stabilize sRNAs and facilitate regulation of their mRNA targets
J. Bacteriol.
198
3309-3317
2016
Escherichia coli (P05055), Escherichia coli
Maeda, T.; Tanaka, Y.; Wachi, M.; Inui, M.
Polynucleotide phosphorylase, RNase E/G, and YbeY are involved in the maturation of 4.5S RNA in Corynebacterium glutamicum
J. Bacteriol.
199
e00798
2017
Corynebacterium glutamicum (Q8NP50), Corynebacterium glutamicum, Corynebacterium glutamicum DSM 20300 (Q8NP50)
Shepherd, D.L.; Hathaway, Q.A.; Pinti, M.V.; Nichols, C.E.; Durr, A.J.; Sreekumar, S.; Hughes, K.M.; Stine, S.M.; Martinez, I.; Hollander, J.M.
Exploring the mitochondrial microRNA import pathway through polynucleotide phosphorylase (PNPase)
J. Mol. Cell. Cardiol.
110
15-25
2017
Mus musculus (Q8K1R3), Mus musculus, Homo sapiens (Q8TCS8), Homo sapiens
html completed
