Organism | UniProt | Comment | Textmining |
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Escherichia coli K-12 | - |
- |
- |
Escherichia coli K-12 CA244 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | PNPase specifically binds a synthetic RNA containing the oxidative lesion 8-hydroxyguanine, PNPase binds to RNA molecules of natural sequence that are oxidatively damaged by treatment with hydrogen peroxide, PNPase binds oxidized RNA with higher affinity than untreated RNA of the same sequence | Escherichia coli K-12 | ? | - |
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additional information | PNPase specifically binds a synthetic RNA containing the oxidative lesion 8-hydroxyguanine, PNPase binds to RNA molecules of natural sequence that are oxidatively damaged by treatment with hydrogen peroxide, PNPase binds oxidized RNA with higher affinity than untreated RNA of the same sequence | Escherichia coli K-12 CA244 | ? | - |
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Synonyms | Comment | Organism |
---|---|---|
PNPase | - |
Escherichia coli K-12 |
polynucleotide phosphorylase | - |
Escherichia coli K-12 |
General Information | Comment | Organism |
---|---|---|
malfunction | PNPase-deficient mutant is hypersensitive to oxidative challenges | Escherichia coli K-12 |
physiological function | PNPase primarily functions in exonucleolytic degradation of RNA in the 3'->5' direction, PNPase also functions in minimizing oxidized RNA in vivo | Escherichia coli K-12 |