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Information on EC 1.3.99.5 - 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)

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IUBMB Comments
A flavoprotein. This bacterial enzyme, characterized from Comamonas testosteroni, is involved in androsterone degradation. cf. EC 1.3.1.22, 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+).
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
5alpha-reductase, srd5a2, srd5a1, 5alpha-r, steroid 5alpha-reductase, 5alpha-reductase type 2, 5alpha-reductase type 1, 5alphar1, 5alpha reductase, 5alphar2, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
a 3-oxo-5alpha-steroid + acceptor = a 3-oxo-DELTA4-steroid + reduced acceptor
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