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Information on EC 1.3.99.5 - 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)

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IUBMB Comments
A flavoprotein. This bacterial enzyme, characterized from Comamonas testosteroni, is involved in androsterone degradation. cf. EC 1.3.1.22, 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+).
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
3-keto-DELTA4-steroid-5 alpha-reductase, 3-ketosteroid-DELTA4(5alpha)-dehydrogenase, 3-oxo-5alpha-steroid DELTA4-dehydrogenase, 3-oxo-steroid-4-ene dehydrogenase, 3-oxosteroid DELTA4-dehydrogenase, 4-ene-3-ketosteroid-5alpha-oxidoreductase, 5 alpha-SR2, 5-alpha reductase II, 5alpha reductase, 5alpha-R, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a 3-oxo-5alpha-steroid + acceptor = a 3-oxo-DELTA4-steroid + reduced acceptor
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