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Literature summary for 1.3.99.5 extracted from
- Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase (2005), J. Steroid Biochem. Mol. Biol., 93, 269-276.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| progesterone + reduced acceptor | Mus musculus | - |
5alpha-pregnan-3,20-dione + acceptor | - |
? |  |
| testosterone + reduced acceptor | Mus musculus | - |
5alpha-dihydrotestosterone + acceptor | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adrenal gland | abnormally high expression of isoform 2 enzyme in male and female | Mus musculus | - |
| prostate gland | type 2 5alpha-reductase mRNA is predominantly expressed in the prostate gland | Mus musculus | - |
| uterus | type 1 5alpha-reductase is predominantly expressed in the uterus | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| progesterone + reduced acceptor | - |
Mus musculus | 5alpha-pregnan-3,20-dione + acceptor | - |
? | |
| testosterone + reduced acceptor | - |
Mus musculus | 5alpha-dihydrotestosterone + acceptor | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| type 2 5alpha-reductase | - |
Mus musculus |
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Release 2023.1 (January 2023)
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