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Literature summary for 1.3.99.5 extracted from

  • Festuccia, C.; Angelucci, A.; Gravina, G.L.; Muzi, P.; Vicentini, C.; Bologna, M.
    Effects of 5 alpha reductase inhibitors on androgen-dependent human prostatic carcinoma cells (2005), J. Cancer Res. Clin. Oncol., 131, 243-254.
    View publication on PubMed

Application

Application Comment Organism
medicine therapeutic potential of enzyme inhibitors MK386 and MK906 to reduce growth and progression of prostatic cancer Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
MK386 significant decrease in cell proliferation of enzyme-positive prostate cancer cell lines Homo sapiens
MK906 significant decrease in cell proliferation of enzyme-positive prostate cancer cell lines Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
BPH-1 cell enzyme-positive prostate cancer cell line, enzyme can be lost in long-term culture Homo sapiens
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LNCaP cell enzyme-positive prostate cancer cell line, enzyme can be lost in long-term culture Homo sapiens
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prostate gland prostate cancer cell lines Homo sapiens
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