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Literature summary for 1.3.99.5 extracted from

  • Gupta, S.; Wang, Y.; Ramos-Garcia, R.; Shevrin, D.; Nelson, J.B.; Wang, Z.
    Inhibition of 5alpha-reductase enhances testosterone-induced expression of U19/Eaf2 tumor suppressor during the regrowth of LNCaP xenograft tumor in nude mice (2010), Prostate, 70, 1575-1585.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
dutasteride
-
Homo sapiens
finasteride
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell
-
Homo sapiens
-
prostate
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
5alpha-reductase
-
Homo sapiens

General Information

General Information Comment Organism
physiological function inhibition of 5alpha-reductase by dutasteride following castration during human LNCaP tumor regrowth in mice enhances the expression of U19/Eaf2, an androgen-regulated tumor suppressor, real-time RT-PCR expression analysis of genes in response to 5alpha-reductase inhibition, detailed overview Homo sapiens