6.3.3.3: dethiobiotin synthase

This is an abbreviated version!
For detailed information about dethiobiotin synthase, go to the full flat file.

Word Map on EC 6.3.3.3

Reaction

ATP
+
7,8-diaminononanoate
+
CO2
=
ADP
+
phosphate
+
dethiobiotin

Synonyms

Synthetase, dethiobiotin, Desthiobiotin synthetase, Dethiobiotin synthetase, DTB synthetase, DTBS, Dethiobiotin synthase, BIO3, BioD, BioD1

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.3 Cyclo-ligases
                6.3.3.3 dethiobiotin synthase

KM Value

KM Value on EC 6.3.3.3 - dethiobiotin synthase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.015 - 0.03
(7R,8S)-7,8-diaminopelargonic acid
0.0013 - 0.045
7,8-diaminononanoate
0.005 - 0.42
ATP
3.4 - 10
CO2
0.025 - 1.09
CTP
0.026 - 1.56
GTP
0.018
ITP
wild-type, pH 7.5, 37°C
0.6
Mg2+
-
-
0.384 - 10.385
NaHCO3
0.023
TTP
wild-type, pH 7.5, 37°C
0.026
UTP
wild-type, pH 7.5, 37°C
additional information
additional information
-
-
-