6.3.3.3: dethiobiotin synthase

This is an abbreviated version!
For detailed information about dethiobiotin synthase, go to the full flat file.

Word Map on EC 6.3.3.3

Reaction

ATP
+
7,8-diaminononanoate
+
CO2
=
ADP
+
phosphate
+
dethiobiotin

Synonyms

Synthetase, dethiobiotin, Desthiobiotin synthetase, Dethiobiotin synthetase, DTB synthetase, DTBS, Dethiobiotin synthase, BIO3, BioD, BioD1

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.3 Cyclo-ligases
                6.3.3.3 dethiobiotin synthase

Purification

Purification on EC 6.3.3.3 - dethiobiotin synthase

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
active site mutant enzymes: T11V, E12A, E12D, K15Q, K37L, K37Q, K37R, S41A, S41C, overproduced in Escherichia coli
-
recombinant DTBS, ammonium sulfate, Sephacryl S-200, Q-Sepharose
-