6.3.3.3: dethiobiotin synthase

This is an abbreviated version!
For detailed information about dethiobiotin synthase, go to the full flat file.

Word Map on EC 6.3.3.3

6.3.3.3

7,8-diaminopelargonic

aminotransferase

dapas

penultimate

ureido

carbamate

diaminopelargonic

Reaction

Synonyms

BIO3, BioD, BioD1, Desthiobiotin synthetase, Dethiobiotin synthase, Dethiobiotin synthetase, DTB synthetase, DTBS, Synthetase, dethiobiotin

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.3 Cyclo-ligases

6.3.3.3 dethiobiotin synthase

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Results	in table
23520	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
1	Cofactor
12	Crystallization (Commentary)
9	IC50 Value
28	Inhibitors
3	Ki Value [mM]
43	KM Value [mM]
1	Localization
9	Metals/Ions
4	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
42	Organism
6	Pathway
158	PDB ID
2	pH Optimum
6	Protein Variants
9	Purification (Commentary)
7	Reaction
2	Reaction Type
42	Reference
2	Source Tissue
6	Specific Activity [micromol/min/mg]
2	Storage Stability
86	Substrates and Products (Substrate)
6	Subunits
16	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
28	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 6.3.3.3 - dethiobiotin synthase

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ADP + 7,8-diaminononanoate + CO2

AMP + phosphate + dethiobiotin

2 entries

ATP + (7R,8S)-7,8-diaminopelargonic acid + NaHCO3

ADP + phosphate + dethiobiotin + Na+ + OH-

3 entries

ATP + 7,8-diaminononanoate + CO2

Escherichia coli

penultimate enzyme of biotin biosynthesis

1339, 1340, 1343, 1346

ATP + 7,8-diaminononanoate + CO2

ADP + phosphate + dethiobiotin

48 entries

ATP + diaminobiotin + CO2

ADP + phosphate + biotin

4 entries

CTP + (7R,8S)-7,8-diaminopelargonic acid + NaHCO3

CDP + phosphate + dethiobiotin + Na+ + OH-

3 entries

CTP + 7,8-diaminononanoate + CO2

CDP + phosphate + dethiobiotin

3 entries

GTP + (7R,8S)-7,8-diaminopelargonic acid + NaHCO3

GDP + phosphate + dethiobiotin + Na+ + OH-

3 entries

GTP + 7,8-diaminononanoate + CO2

GDP + phosphate + dethiobiotin

Pseudomonas graveolens

1335

ITP + (7R,8S)-7,8-diaminopelargonic acid + NaHCO3

IDP + phosphate + dethiobiotin + Na+ + OH-

3 entries

ITP + 7,8-diaminononanoate + CO2

IDP + phosphate + dethiobiotin

3 entries

TTP + (7R,8S)-7,8-diaminopelargonic acid + NaHCO3

TDP + phosphate + dethiobiotin + Na+ + OH-

3 entries

UTP + (7R,8S)-7,8-diaminopelargonic acid + NaHCO3

UDP + phosphate + dethiobiotin + Na+ + OH-

2 entries

UTP + 7,8-diaminononanoate + CO2

UDP + phosphate + dethiobiotin

3 entries