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6.3.3.3: dethiobiotin synthase

This is an abbreviated version!
For detailed information about dethiobiotin synthase, go to the full flat file.

Word Map on EC 6.3.3.3

Reaction

ATP
+
7,8-diaminononanoate
 +
CO2
=
ADP
 +
phosphate
 +
dethiobiotin

Synonyms

BIO3, BioD, BioD1, Desthiobiotin synthetase, Dethiobiotin synthase, Dethiobiotin synthetase, DTB synthetase, DTBS, Synthetase, dethiobiotin

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.3 Cyclo-ligases
                6.3.3.3 dethiobiotin synthase

Inhibitors

Inhibitors on EC 6.3.3.3 - dethiobiotin synthase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
Pseudomonas graveolens
-
-
2,2'-dipyridyl
Pseudomonas graveolens
-
-
6-hydroxypyrimidin-4(3H)-one
-
competitive inhibition
7,8-diaminononanoate
Pseudomonas graveolens
-
competitive to diaminobiotin
adenine
-
-
Ag+
-
1 mM, 100% inhibition
AMP-PNP
-
-
Cd2+
-
1 mM, 70% inhibition
Co2+
-
1 mM, 35% inhibition
Cu2+
-
1 mM, 100% inhibition
dethiobiotin
-
10 mM, 30% inhibition
Diaminobiotin
Pseudomonas graveolens
-
competitive to 7,8-diaminononanoate
EDTA
Pseudomonas graveolens
-
-
Hg2+
-
1 mM, 100% inhibition
Ni2+
-
1 mM, 80% inhibition