6.3.3.3: dethiobiotin synthase

This is an abbreviated version!
For detailed information about dethiobiotin synthase, go to the full flat file.

Word Map on EC 6.3.3.3

Reaction

ATP
+
7,8-diaminononanoate
+
CO2
=
ADP
+
phosphate
+
dethiobiotin

Synonyms

Synthetase, dethiobiotin, Desthiobiotin synthetase, Dethiobiotin synthetase, DTB synthetase, DTBS, Dethiobiotin synthase, BIO3, BioD, BioD1

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.3 Cyclo-ligases
                6.3.3.3 dethiobiotin synthase

IC50 Value

IC50 Value on EC 6.3.3.3 - dethiobiotin synthase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.349 - 0.437
ATP
0.054 - 5.752
CTP
0.597 - 2
GTP
0.52
ITP
Mycobacterium tuberculosis
wild-type, pH 7.5, 37°C
0.622
TTP
Mycobacterium tuberculosis
wild-type, pH 7.5, 37°C
0.634
UTP
Mycobacterium tuberculosis
wild-type, pH 7.5, 37°C