4.1.1.50: adenosylmethionine decarboxylase
This is an abbreviated version!
For detailed information about adenosylmethionine decarboxylase, go to the full flat file.
Word Map on EC 4.1.1.50
-
4.1.1.50
-
polyamine
-
spermidine
-
putrescine
-
methylglyoxal
-
bisguanylhydrazone
-
diamine
-
alpha-difluoromethylornithine
-
brucei
-
prostate
-
decarboxylases
-
l-ornithine
-
trypanosoma
-
n1-acetyltransferase
-
antiproliferative
-
proenzyme
-
pyruvoyl
-
aminopropyltransferases
-
agmatine
-
agriculture
-
1,3-diaminopropane
-
synthesis
-
pentamidine
-
trypanosomatids
-
n1-acetylspermidine
-
medicine
-
pao
-
pharmacology
-
adenosyltransferase
-
antizyme
-
dl-alpha-difluoromethylornithine
-
glyoxal
-
drought
-
rhodesiense
-
trypanosomiasis
-
analysis
-
trypanothione
-
guanylhydrazone
-
difluoromethylornithine
-
uorfs
-
normfinder
-
methylthioadenosine
-
biotechnology
-
arginase
-
polyamine-depleted
-
cadaverine
-
genorm
-
berenil
-
enzyme-activated
- 4.1.1.50
- polyamine
- spermidine
- putrescine
- methylglyoxal
- bisguanylhydrazone
- diamine
- alpha-difluoromethylornithine
- brucei
- prostate
- decarboxylases
- l-ornithine
- trypanosoma
-
n1-acetyltransferase
-
antiproliferative
- proenzyme
-
pyruvoyl
- aminopropyltransferases
- agmatine
- agriculture
- 1,3-diaminopropane
- synthesis
- pentamidine
-
trypanosomatids
- n1-acetylspermidine
- medicine
- pao
- pharmacology
-
adenosyltransferase
- antizyme
- dl-alpha-difluoromethylornithine
- glyoxal
- drought
- rhodesiense
- trypanosomiasis
- analysis
- trypanothione
-
guanylhydrazone
- difluoromethylornithine
-
uorfs
-
normfinder
- methylthioadenosine
- biotechnology
- arginase
-
polyamine-depleted
- cadaverine
-
genorm
- berenil
-
enzyme-activated
Reaction
Synonyms
Ado-MetDC, AdoMet decarboxylase, AdoMetDC, AdoMetDC/ODC, AMDC, BjSAMDC1, BjSAMDC2, BjSAMDC3, BjSAMDC4, BlsE, Bud2, MdSAMDC1, MdSAMDC2, OsSAMDC, PfAdoMetDC, protein SSO0585, S-adenosyl methionine decarboxylase, S-Adenosyl-L-methionine decarboxylase, S-adenosyl-methionine-decarboxylase, S-adenosylmethionine decarboxy-lase/ornithine decarboxylase, S-Adenosylmethionine decarboxylase, S-adenosylmethionine decarboxylase 1, S-adenosylmethionine decarboxylase 2, S-adenosylmethionine decarboxylase 3, S-adenosylmethionine decarboxylase 4, SAM decarboxylase, SAM-DC, SAMDC, SvPEPC, Tb927.6.4410
ECTree
4.1.1.50 adenosylmethionine decarboxylaseAdvanced search results
results (
results (Natural Substrates Products
Natural Substrates Products on EC 4.1.1.50 - adenosylmethionine decarboxylase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
S-adenosyl-L-methionine
(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
-
-
-
?
S-adenosyl-L-methionine
(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
-
-
?
S-adenosyl-L-methionine
(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
-
-
?
S-adenosyl-L-methionine
?
-
key enzyme in the biosynthetic pathway for spermidine and spermine
-
-
?
S-adenosyl-L-methionine
?
-
the enzyme protein turns over very rapidly in growing or differentiating tissues
-
-
?
S-adenosyl-L-methionine
?
-
key enzyme in the biosynthetic pathway for spermidine and spermine
-
-
?
S-adenosyl-L-methionine
?
-
key enzyme in the biosynthetic pathway for spermidine and spermine
-
-
?
S-adenosyl-L-methionine
?
-
the enzyme protein turns over very rapidly in growing or differentiating tissues
-
-
?
S-adenosyl-L-methionine
?
-
key enzyme in the biosynthetic pathway for spermidine and spermine
-
-
?
S-adenosyl-L-methionine
?
-
key enzyme in the biosynthetic pathway for spermidine and spermine
-
-
?
S-adenosyl-L-methionine
?
-
major regulatory enzyme in polyamine biosynthesis
-
-
?
S-adenosyl-L-methionine
?
-
the enzyme protein turns over very rapidly in growing or differentiating tissues
-
-
?
S-adenosyl-L-methionine
?
-
key enzyme in the biosynthetic pathway for spermidine and spermine
-
-
?
S-adenosyl-L-methionine
?
-
the enzyme protein turns over very rapidly in growing or differentiating tissues
-
-
?
S-adenosyl-L-methionine
?
-
major regulatory enzyme in polyamine biosynthesis
-
-
?
S-adenosyl-L-methionine
?
-
key enzyme in the biosynthetic pathway for spermidine and spermine
-
-
?
S-adenosyl-L-methionine
?
-
EC 4.1.1.50 and EC 2.5.1.16 appear to function in sequence in animals and microorganisms in the synthesis of spermidine
-
-
?
S-adenosyl-L-methionine
S-adenosyl 3-(methylthio)propylamine + CO2
-
-
-
-
?
S-adenosyl-L-methionine
S-adenosyl 3-(methylthio)propylamine + CO2
-
-
-
?
S-adenosyl-L-methionine
S-adenosyl 3-(methylthio)propylamine + CO2
-
-
-
-
?
S-adenosyl-L-methionine
S-adenosyl 3-(methylthio)propylamine + CO2
-
-
-
?
S-adenosyl-L-methionine
S-adenosyl 3-(methylthio)propylamine + CO2
-
-
-
-
?
additional information
?
-
key enzyme involved in polyamine biosynthetic pathway
-
-
?
additional information
?
-
key enzyme involved in polyamine biosynthetic pathway
-
-
?
additional information
?
-
key enzyme involved in polyamine biosynthetic pathway
-
-
?
additional information
?
-
key enzyme involved in polyamine biosynthetic pathway
-
-
?
additional information
?
-
-
adhesion-dependent expression of S-adenosylmethionine decarboxylase contributes to extracellular matrix-dependent differentiation of human salivary gland epithelial cells
-
-
?
additional information
?
-
MdSAMDC2 is mainly involved in stress responses
-
-
?
additional information
?
-
-
MdSAMDC2 is mainly involved in stress responses
-
-
?
additional information
?
-
MdSAMDC1 is mainly involved in fruit development and cell growth
-
-
?
additional information
?
-
-
key rate-controlling enzyme in the synthesis of spermidine and spermine. Overexpression of AdoMetDC does not produce an overt cardiac phenotype, but there is an increased cardiac hypertrophy after beta-adrenergic stimulation, and crosses of alpha-myosin heavy chain/ADoMetDC mice with alpha-myosin heavy chain/ornithine decarboxylase mice are lethal at an early embryonic stage
-
-
?
additional information
?
-
-
S-adenosyl-L-methionine decarboxylase gene of cold-tolerant japonica cultivar Yukihikari and cold-susceptible indica variety TKM9 is differentially expressed under low temperature stress. Upon exposure to cold stress (5°C) the level of OsSAMDC transcripts in the cold-resistant Yukihihari genotype continues to increase for up to 72 h. There is no change in OsSAMDC transcription in the cold-susceptible indica cultivar TLM9 under the same conditions
-
-
?
additional information
?
-
-
synthesis of the triamine spermidine and the tetramine spermine is achieved by the sequential addition of aminopropyl moieties from decarboxylated S-adenosylmethionine, synthesized by the enzyme S-adenosylmethionine decarboxylase
-
-
?
additional information
?
-
-
critical regulatory enzyme of the polyamine biosynthetic pathway
-
-
?
