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4.1.1.50: adenosylmethionine decarboxylase

This is an abbreviated version!
For detailed information about adenosylmethionine decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.50

Reaction

S-adenosyl-L-methionine
=
S-adenosyl 3-(methylsulfanyl)propylamine
 +
CO2

Synonyms

Ado-MetDC, AdoMet decarboxylase, AdoMetDC, AdoMetDC/ODC, AMDC, BjSAMDC1, BjSAMDC2, BjSAMDC3, BjSAMDC4, BlsE, Bud2, MdSAMDC1, MdSAMDC2, OsSAMDC, PfAdoMetDC, protein SSO0585, S-adenosyl methionine decarboxylase, S-Adenosyl-L-methionine decarboxylase, S-adenosyl-methionine-decarboxylase, S-adenosylmethionine decarboxy-lase/ornithine decarboxylase, S-Adenosylmethionine decarboxylase, S-adenosylmethionine decarboxylase 1, S-adenosylmethionine decarboxylase 2, S-adenosylmethionine decarboxylase 3, S-adenosylmethionine decarboxylase 4, SAM decarboxylase, SAM-DC, SAMDC, SvPEPC, Tb927.6.4410

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.50 adenosylmethionine decarboxylase

IC50 Value

IC50 Value on EC 4.1.1.50 - adenosylmethionine decarboxylase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.2 - 104
3-[(E)-[(2E)-[amino[(2E)-2-[3-[amino(imino)methyl]benzylidene]hydrazino]methylene]hydrazono]methyl]benzenecarboximidamide
0.0006
5'-deoxy-5'-(N,N-dimethylamino)-8-methyladenosine
Homo sapiens
-
0.009
5'-deoxy-5'-(N,N-dimethylamino)adenosine
Homo sapiens
-
0.003
5'-deoxy-5'-dimethylsulfonio-8-methyladenosine chloride
Homo sapiens
-
0.015
5'-deoxy-5'-dimethylsulfonioadenosine chloride
Homo sapiens
-
0.00017
5'-deoxy-5'-[(2-hydrazinocarbonylethyl)methylamino]-8-methyladenosine
Homo sapiens
-
0.0015
5'-deoxy-5'-[(2-hydrazinocarbonylethyl)methylamino]-adenosine sulfate
Homo sapiens
-
0.157
5'-deoxy-5'-[(2-hydroxyamidinoethyl)methylamino]adenosine
Homo sapiens
-
0.031
5'-deoxy-5'-[(hydrazinocarbonylmethyl)methylamino]-8-methyladenosine
Homo sapiens
-
0.088
5'-[(2-aminoethyl)methylamino]-5'-deoxy-8-methyladenosine
Homo sapiens
-
0.000086
5'-[(2-aminooxyethyl)methylamino]-5'-deoxy-8-(methylamino)adenosine sulfate
Homo sapiens
-
0.000007
5'-[(2-aminooxyethyl)methylamino]-5'-deoxy-8-methyladenosine sulfate
Homo sapiens
-
0.000055
5'-[(2-aminooxyethyl)methylamino]-5'-deoxyadenosine
Homo sapiens
-
0.004
5'-[(2-carboxamidoethyl)methyamino]-5'-deoxy-8-ethyladenosine sulfate
Homo sapiens
-
0.0004
5'-[(2-carboxamidoethyl)methylamino]-5'-deoxy-8-methyladenosine sulfate
Homo sapiens
-
0.007
5'-[(2-carboxamidoethyl)methylamino]-5'-deoxyadenosine sulfate
Homo sapiens
-
0.44
5'-[(3-aminopropyl)methylamino]-5'-deoxy-8-(methylamino)adenosine sulfate
Homo sapiens
-
0.42
5'-[(3-aminopropyl)methylamino]-5'-deoxy-8-ethyladenosine sulfate
Homo sapiens
-
0.07
5'-[(3-aminopropyl)methylamino]-5'-deoxy-8-methyladenosine sulfate
Homo sapiens
-
0.5
5'-[(3-aminopropyl)methylamino]-5'-deoxyadenosine sulfate
Homo sapiens
-
0.000049
5'-[(4-aminooxybutyl)methylamino]-5'-deoxy-8-(methylamino)adenosine sulfate
Homo sapiens
-
0.000015
5'-[(4-aminooxybutyl)methylamino]-5'-deoxy-8-ethyladenosine sulfate
Homo sapiens
-
0.000005
5'-[(4-aminooxybutyl)methylamino]-5'-deoxy-8-methyladenosine sulfate
Homo sapiens
-
0.000011
5'-[(4-aminooxybutyl)methylamino]-5'-deoxy-8-oxoadenosine sulfate
Homo sapiens
-
0.000018
5'-[(4-aminooxybutyl)methylamino]-5'-deoxyadenosine sulfate
Homo sapiens
-
0.001
MDL73811
Plasmodium falciparum
-
-
0.0019
N4-(3,5-dibromophenyl)-6-methylpyrimidine-2,4-diamine
Trypanosoma brucei brucei
pH 7.2, temperature not specified in the publication
0.0015
N4-(3,5-dichloro-4-fluorophenyl)-6-methylpyrimidine-2,4-diamine
Trypanosoma brucei brucei
pH 7.2, temperature not specified in the publication