Crystallization (Comment) | Organism |
---|---|
hanging drop vapour diffusion method, structures of the wild-type proenzyme and the S63A mutant at 1.55 A and 1.7 A resolution | Thermotoga maritima |
Protein Variants | Comment | Organism |
---|---|---|
C83A | mutant proenzyme is cleaved more rapidly than the wild-type enzyme | Thermotoga maritima |
H68A | mutant proenzyme is cleaved much more slowly than the wild-type enzyme | Thermotoga maritima |
S55A | mutant proenzyme is cleaved more rapidly than the wild-type enzyme | Thermotoga maritima |
S63A | the mutation traps the enzyme in the proenzyme form | Thermotoga maritima |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Thermotoga maritima | critical regulatory enzyme of the polyamine biosynthetic pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermotoga maritima | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Thermotoga maritima |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | critical regulatory enzyme of the polyamine biosynthetic pathway | Thermotoga maritima | ? | - |
? |