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Literature summary for 4.1.1.50 extracted from

  • Greco, A.; Calle, A.; Morfin, F.; Thouvenot, D.; Cayre, M.; Kindbeiter, K.; Martin, L.; Levillain, O.; Diaz, J.J.
    S-adenosyl methionine decarboxylase activity is required for the outcome of herpes simplex virus type 1 infection and represents a new potential therapeutic target (2005), FASEB J., 19, 1128-1130.
    View publication on PubMed

Application

Application Comment Organism
medicine S-adenosyl methionine decarboxylase activity is required for the outcome of herpes simplex virus type 1 infection and represents a new potential therapeutic target, inhibition of the enzyme by methylglyoxal bis(guanylhydrazone) prevents HSV-1 infection Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
methylglyoxal bis(guanylhydrazone)
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens key enzyme of polyamine biosynthetic pathway ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information key enzyme of polyamine biosynthetic pathway Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
SAMDC
-
Homo sapiens