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4.1.1.37: uroporphyrinogen decarboxylase

This is an abbreviated version!
For detailed information about uroporphyrinogen decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.37

Reaction

uroporphyrinogen III
=
Coproporphyrinogen III
 + 4 CO2

Synonyms

ch-UroD, Decarboxylase, uroporphyrinogen, Hem12p, PCL, Porphyrinogen carboxy-lyase, rl-UroD, tobacco UROD, UORO-D, UPD, URO-D, Uro-decarboxylase, uro-III decarboxylase, UroD, UROD protein, UROD1, uroporphyrinogen decarboxylase, uroporphyrinogen decarboxylase 1, Uroporphyrinogen III decarboxylase, uroporphyrinogen-decarboxylase, uroporphyrinogen-III decarboxylase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.37 uroporphyrinogen decarboxylase

pH Range

pH Range on EC 4.1.1.37 - uroporphyrinogen decarboxylase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5 - 6.6
-
pH 5.0: about 80% of maximal activity, pH 6.6: about 40% of maximal activity, 5-COOH-porphyrinogen I
5 - 8
-
in 0.2 M KH2PO4, 0.1 mM dithiothreitol
5.3 - 8
-
pH 5.3: about 60% of maximal activity, pH 8.0: about 65% of maximal activity
5.8 - 7.4
-
pH 5.8: about 65% of maximal activity, pH 7.4: about 45% of maximal activity, uroporphyrinogen I
5.8 - 7.8
-
pH 5.8: about 60% of maximal activity, pH 7.8: about 55% of maximal activity, 5-COOH-porphyrinogen III
6 - 7.2
-
pH 6.0: about 50% of maximal activity, pH 7.2: about 60% of maximal activity, uroporphyrinogen III
6 - 7.4
-
pH 6.0: about 55% of maximal activity, pH 7.4: about 50% of maximal activity, uroporphyrinogen III
6.1 - 7.9
-
-
6.2 - 7.7
-
pH 6.2: about 25% of maximal activity, pH 7.7: about 70% of maximal activity
6.4 - 7.9
-
-