4.1.1.37: uroporphyrinogen decarboxylase

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For detailed information about uroporphyrinogen decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.37

4.1.1.37

porphyria

cutanea

tarda

heme

erythrocyte

porphyrinogenic

hexachlorobenzene

urinary

hepatoerythropoietic

porphobilinogen

overload

photosensitivity

ferrochelatase

protoporphyrin

hemochromatosis

5-aminolaevulinate

heptacarboxylic

hexachlorobenzene-induced

hypertrichosis

phlebotomy

erythropoietic

delta-aminolaevulinic

polyhalogenated

5-aminolevulinic

protoporphyrinogen

uroporphyria

tetrapyrrole

sun-exposed

blister

siderosis

diagnostics

3,4,3\',4\'-tetrachlorobiphenyl

medicine

hcb-induced

miliae

coproporphyria

bulla

agriculture

hepta

Reaction

+ 4 CO2

Synonyms

ch-UroD, Decarboxylase, uroporphyrinogen, Hem12p, PCL, Porphyrinogen carboxy-lyase, rl-UroD, tobacco UROD, UORO-D, UPD, URO-D, Uro-decarboxylase, uro-III decarboxylase, UroD, UROD protein, UROD1, uroporphyrinogen decarboxylase, uroporphyrinogen decarboxylase 1, Uroporphyrinogen III decarboxylase, uroporphyrinogen-decarboxylase, uroporphyrinogen-III decarboxylase

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.1 Carboxy-lyases

4.1.1.37 uroporphyrinogen decarboxylase

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Results	in table
7	Activating Compound
32364	AA Sequence
10	Application
1	CAS Registry Number
20	Cloned(Commentary)
2	Cofactor
9	Crystallization (Commentary)
1235	Disease/ Diagnostics
1	Expression
5	General Information
3	General Stability
1	IC50 Value
120	Inhibitors
58	KM Value [mM]
8	Localization
3	Metals/Ions
42	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
264	Organism
1	Oxidation Stability
12	Pathway
33	PDB ID
20	pH Optimum
11	pH Range
1	pH Stability
2	pI Value
1	Posttranslational Modification
44	Protein Variants
34	Purification (Commentary)
3	Reaction
2	Reaction Type
77	Reference
43	Source Tissue
27	Specific Activity [micromol/min/mg]
9	Storage Stability
140	Substrates and Products (Substrate)
21	Subunits
69	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
3	Temperature Range [°C]
10	Temperature Stability [°C]
7	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 4.1.1.37 - uroporphyrinogen decarboxylase

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beta-mercaptoethanol

Plasmodium falciparum

absolute requirement for activity

dithiothreitol

EDTA

enhances activity

reduced glutathione

enhances activity

Reducing agents

required