Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

4.1.1.37: uroporphyrinogen decarboxylase

This is an abbreviated version!
For detailed information about uroporphyrinogen decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.37

Reaction

uroporphyrinogen III
=
Coproporphyrinogen III
+ 4 CO2

Synonyms

ch-UroD, Decarboxylase, uroporphyrinogen, Hem12p, PCL, Porphyrinogen carboxy-lyase, rl-UroD, tobacco UROD, UORO-D, UPD, URO-D, Uro-decarboxylase, uro-III decarboxylase, UroD, UROD protein, UROD1, uroporphyrinogen decarboxylase, uroporphyrinogen decarboxylase 1, Uroporphyrinogen III decarboxylase, uroporphyrinogen-decarboxylase, uroporphyrinogen-III decarboxylase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.37 uroporphyrinogen decarboxylase

Crystallization

Crystallization on EC 4.1.1.37 - uroporphyrinogen decarboxylase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
hanging drop vapour diffusion with 25% polyethylene glycol-monomethyl ether 2000 and 160 mM sodium acetate in 100 mM citrate, pH 5.6, at 20°C
-
crystallized in complex with coproporphyrinogen by sitting drop vapor diffusion, crystals belong to space group P3(1)21, unit cell dimensions a : b :102.9 A, c : 74.5 A
modified enzyme single-chain URO-D crystals are isomorphous with wild-type uroporphyrinogen decarboxylase crystals
mutant URO-D proteins G156D, F232L, and I260T
recombinant mutant proteins K297N and G318R
hanging drop vapor diffusion method, space group P622,unit cell constants a : b : 158.44 A, c : 67.68 A
-
hexagonal space group P622, unit cell parameters a : b : 158.44 A, c : 67.68 A
-