3.6.1.7: acylphosphatase
This is an abbreviated version!
For detailed information about acylphosphatase, go to the full flat file.
Word Map on EC 3.6.1.7
-
3.6.1.7
-
horse
-
native-like
-
ca2+-atpase
-
solfataricus
-
trifluoroethanol
-
phosphoenzyme
-
acylphosphates
-
thioflavine
-
ototoxicity
-
amyloid-like
-
protofibrils
-
medicine
- 3.6.1.7
- horse
-
native-like
- ca2+-atpase
- solfataricus
- trifluoroethanol
- phosphoenzyme
- acylphosphates
-
thioflavine
- ototoxicity
-
amyloid-like
-
protofibrils
- medicine
Reaction
Synonyms
1,3-diphosphoglycerate phosphatase, acetic phosphatase, acetyl phosphatase, acetylphosphatase, ACP, AcPDRo2, acyl phosphatase, acyl phosphate phosphohydrolase, Acylphosphatase, erythrocyte isozyme, Acylphosphatase, erythrocyte/testis isozyme, Acylphosphate phosphohydrolase, acylphosphate phosphomonohydrolase, Acyp, ACYP2, carbamoylphosphate phosphatase, carbamyl phosphate phosphatase, Ch1, Ch2, GP 1-3, GP1, GP2, GP3, Ho 1-3, Ho1, Ho2, Ho3, human common-type acylphosphatase, Isozyme CH1, Isozyme CH2, Isozyme TU1, More, muscle-type acylphosphatase 2, native acylphosphatase, PhAcP, phosphatase, acyl, Sso AcP, SSO0887, T1, TT0497
ECTree
3.6.1.7 acylphosphataseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 3.6.1.7 - acylphosphatase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1,3-bisphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
nucleoside triphosphate + H2O
nucleoside diphosphate + phosphate
-
-
-
?
(Ca2+-Mg2+)-ATPase phosphorylated intermediate + H2O
?
-
phospho-aspartyl intermediate
-
-
?
(Ca2+-Mg2+)-ATPase phosphorylated intermediate + H2O
?
-
acylphosphorylated intermediates of Ca2+-ATPase from skeletal muscle sarcoplasmic reticulum and heart sarcolemma
-
-
?
(Ca2+-Mg2+)-ATPase phosphorylated intermediate + H2O
?
-
acylphosphate bond in phosphorylated intermediate
-
-
?
(Ca2+-Mg2+)-ATPase phosphorylated intermediate + H2O
?
-
erythrocyte type enzyme, acylphosphorylated intermediates from human erythrocyte membrane
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
1,3-diphosphoglycerate can acylate histones, particularly the lysine-rich ones, 1,3-diphosphoglycerate phosphatase can prevent this acylation
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
carbamoyl phosphate and 1,3-diphosphoglycerate can acylate and carbamylate some proteins, acyl phosphatase could prevent such acylation and carbamylation, exerting a regulatory role on the intracellular concentration of 1,3-diphosphoglycerate and carbamoyl phosphate
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
possible physiological substrate
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
1,3-diphosphoglycerate can acylate histones, particularly the lysine-rich ones, 1,3-diphosphoglycerate phosphatase can prevent this acylation
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
1,3-diphosphoglycerate can acylate histones, particularly the lysine-rich ones, 1,3-diphosphoglycerate phosphatase can prevent this acylation
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
1,3-diphosphoglycerate can acylate histones, particularly the lysine-rich ones, 1,3-diphosphoglycerate phosphatase can prevent this acylation
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
1,3-diphosphoglycerate can acylate histones, particularly the lysine-rich ones, 1,3-diphosphoglycerate phosphatase can prevent this acylation
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
1,3-diphosphoglycerate can acylate histones, particularly the lysine-rich ones, 1,3-diphosphoglycerate phosphatase can prevent this acylation
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
-
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
possible physiological substrate
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
1,3-diphosphoglycerate + H2O
3-phosphoglycerate + phosphate
-
1,3-diphosphoglycerate can acylate histones, particularly the lysine-rich ones, 1,3-diphosphoglycerate phosphatase can prevent this acylation
-
-
?
acetyl phosphate + H2O
acetate + phosphate
-
-
-
-
?
acetyl phosphate + H2O
acetate + phosphate
-
-
-
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
erythrocyte isoenzyme shows hydrolytic activity on acyl phosphates with higher affinity than the muscle enzyme
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
hydrolysis of acylphosphates both synthetic and physiologically relevant
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
acylphosphate + H2O
carboxylate + phosphate
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
?
benzoyl phosphate + H2O
benzoate + phosphate
-
-
-
-
?
benzoyl phosphate + H2O
benzoate + phosphate
-
-
-
-
?
benzoyl phosphate + H2O
benzoate + phosphate
-
-
-
-
?
benzoyl phosphate + H2O
benzoate + phosphate
-
-
-
-
?
benzoyl phosphate + H2O
benzoate + phosphate
-
-
-
-
?
benzoyl phosphate + H2O
benzoate + phosphate
-
-
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
-
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
-
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
muscle enzyme, poor substrate
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
carbamoyl phosphate and 1,3-diphosphoglycerate can acylate and carbamylate some proteins, acyl phosphatase could prevent such acylation and carbamylation, exerting a regulatory role on the intracellular concentration of 1,3-diphosphoglycerate and carbamoyl phosphate
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
liver enzyme, carbamoyl phosphate can reach high concentrations in liver and its level may be partly controlled by acyl phosphatase
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
possible physiological substrate
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
-
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
erythrocyte enzyme: not a substrate
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
acylphosphatase could have a function of controlling the intracellular levels of carbamoylphosphate by preventing the accumulation of this compound mainly in those tissues lacking the urea cycle enzymes. It could avoid the carbamylation of many proteins which results in modifications, inhibition of their functional properties
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
role in pyrimidine biosynthesis
-
-
?
carbamoyl phosphate + H2O
carbamate + phosphate
-
possible physiological substrate
-
-
?
diphosphate + H2O
2 phosphate
-
erythrocyte enzyme, inorganic diphosphate: not a substrate
-
-
?
DNA + H2O
?
-
DNAase activity, nucleolytic activity, exonucleolytic and endonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
DNA + H2O
?
-
muscle type and common type hydrolyze double stranded DNA, high molecular weight human genomic DNA
-
-
?
DNA + H2O
?
-
DNAase activity, nucleolytic activity, exonucleolytic and endonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
DNA + H2O
?
-
endonucleolytic activity on plasmid DNA, pRcCMV plasmid DNA, closed circular plasmid DNA, exonucleolytic activity on linear plasmid DNA
-
-
?
DNA + H2O
?
-
DNAase activity, nucleolytic activity, exonucleolytic and endonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
sarcolemma Na+,K+-ATPase phosphorylated intermediate
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
acylphosphatase significantly enhances the rate of strophantidine-sensitive ATP hydrolysis, it uncouples erythrocyte membrane N+,K+ pump
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
acylphosphatase hydrolyzes phosphoenzyme intermediate of heart sarcolemma Na+,K+-ATPase
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
acylphosphatase increases the rate of Na+,K+-dependent ATP hydrolysis, acylphosphatase significantly stimulates the rate of ATP driven Na+ transport into sarcolemma vesicles: accelerated hydrolysis of the phosphoenzyme may result in an enhanced activity of heart sarcolemma Na+,K+ pump, suggesting a potential role of acylphosphatase in the control of this active transport system
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
acylphosphorylated phosphoenzyme intermediate, enzyme has a high affinity for this substrate
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
acylphosphatase can actively hydrolyze Na+/K+-ATPase phosphoenzyme
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
acylphosphatase produces a modification in the stoichiometry of the ATP driven cation transport by the Na+,K+ pump
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
from erythrocyte membrane
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
acylphosphatase significantly enhances the rate of strophantidine-sensitive ATP hydrolysis, it uncouples erythrocyte membrane N+,K+ pump
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
acylphosphatase markedly affects the functional properties of Na+,K+ pump, notably the rate of ATP hydrolysis and of cation, Na+,Rb+, transport
-
-
?
Na+/K+-ATPase phosphoenzyme intermediate + H2O
?
-
acylphosphorylated phosphoenzyme intermediate, enzyme has a high affinity for this substrate
-
-
?
nucleic acids + H2O
?
-
nucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
nucleic acids + H2O
?
-
nucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
nucleic acids + H2O
?
-
nucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
nucleoside diphosphate + H2O
nucleoside phosphate + phosphate
-
-
-
?
nucleoside diphosphate + H2O
nucleoside phosphate + phosphate
-
-
-
?
p-nitrobenzoyl phosphate + H2O
p-nitrobenzoate + phosphate
-
-
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
liver enzyme, no activity at pH 5.3 and 10.4
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
muscle enzyme, very low activity at pH 5.3, no activity at pH 10.4
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
erythrocyte enzyme, not a substrate
-
-
?
poly (rA) + H2O
?
-
ribonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
poly (rA) + H2O
?
-
ribonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
poly (rA) + H2O
?
-
ribonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
RNA + H2O
?
-
RNAase activity, ribonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
RNA + H2O
?
-
RNAase activity, ribonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
RNA + H2O
?
-
RNAase activity, ribonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
succinoyl phosphate + H2O
succinate + phosphate
-
-
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
acts specifically by splitting off the carboxyl phosphate bond
-
-
?
additional information
?
-
-
nucleolytic, ribonucleolytic and deoxyribonucleolytic, activity, exonucleolytic and endonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
additional information
?
-
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
additional information
?
-
-
nucleolytic activity of muscle and common type isoform acylphosphatase on RNA and DNA is possible physiological activity of these isoenzymes in the cell
-
-
?
additional information
?
-
-
since acylphosphatase hydrolyzes the high-energy phosphorylated compounds its action is probably involved in the regulation of cell energy metabolism
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
additional information
?
-
-
acylphosphatase is active as a nuclease at pH ranging from 5.5 to 6.8 suggests that enzymes could play some role in apoptotic mechanisms
-
-
?
additional information
?
-
-
acylphosphatase increases the rate of Na+,K+-dependent ATP hydrolysis, acylphosphatase significantly stimulates the rate of ATP driven Na+ transport into sarcolemma vesicles: accelerrated hydrolysis of the phosphoenzyme may result in an enhanced activity of heart sarcolemma Na+,K+ pump, suggesting a potential role of acylphosphatase in the control of this active transport system
-
-
?
additional information
?
-
-
acylphosphatase increases the rate of Na+,K+-dependent ATP hydrolysis, acylphosphatase significantly stimulates the rate of ATP driven Na+ transport into sarcolemma vesicles: accelerrated hydrolysis of the phosphoenzyme may result in an enhanced activity of heart sarcolemma Na+,K+ pump, suggesting a potential role of acylphosphatase in the control of this active transport system
-
-
?
additional information
?
-
-
enzyme is thought to regulate metabolic processes in which acylphosphates are involved, such as glycolysis and production of ribonucleotides
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
additional information
?
-
-
acylphosphatase seems to have a regulatory function, controlling the concentrations of highly reactive compounds such as acyl phosphates
-
-
?
additional information
?
-
-
acylphosphatase, a small enzyme that catalyzes the hydrolysis of acylphosphates and participates in ion transport across biological membranes, is involved in genetic incompatibilities leading to male sterility in hybrids between Drosophila simulans and Drosophila mauritiana. There is a strong association between Acyp alleles as genotype and the sterility/fertility pattern as phenotype, as well as between the phenotype, the genotype and its transcriptional activity
-
-
?
additional information
?
-
-
acylphosphatase, a small enzyme that catalyzes the hydrolysis of acylphosphates and participates in ion transport across biological membranes, is involved in genetic incompatibilities leading to male sterility in hybrids between Drosophila simulans and Drosophila mauritiana. There is a strong association between Acyp alleles as genotype and the sterility/fertility pattern as phenotype, as well as between the phenotype, the genotype and its transcriptional activity
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
acts specifically by splitting off the carboxyl phosphate bond
-
-
?
additional information
?
-
-
phosphorylated intermediates of (Ca2+ + Mg2+)-ATPase and phosphorylated peptides obtained by pepsin digestion of labeled phosphorylated microsomes are completely hydrolyzed by acylphosphatase
-
-
?
additional information
?
-
-
liver enzyme and muscle enzyme, no activity with acetyl-AMP, phosphoenolpyruvate and phosvitin
-
-
?
additional information
?
-
-
liver enzyme and muscle enzyme, no activity with acetyl-AMP, phosphoenolpyruvate and phosvitin
-
-
?
additional information
?
-
-
no activity with phosphoenolpyruvate and phosvitin
-
-
?
additional information
?
-
-
carbamoyl phosphate and 1,3-diphosphoglycerate can acylate and carbamylate some proteins, acyl phosphatase could prevent such acylation and carbamylation, exerting a regulatory role on the intracellular concentration of 1,3-diphosphoglycerate and carbamoyl phosphate
-
-
?
additional information
?
-
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
additional information
?
-
-
possible regulatory role of the enzyme in ion transport systems, proceeding via the formation of a phosphorylated protein intermediate with an acylphosphate bond
-
-
?
additional information
?
-
-
hydrolytic activity by this enzyme on the phosphorylated intermediate is possible involved in Ca2+ transport in sarcoplasmic reticulum
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
additional information
?
-
-
enzyme could control acylation and carbamylation of proteins by regulation the levels of reactive acyl and carbamoyl phosphates
-
-
?
additional information
?
-
-
possible role in regulating the glycolytic pathway, ureogenesis and pyrimidine biosynthesis
-
-
?
additional information
?
-
-
possible physiological role for acylphosphatase activity may be regulation of metabolic pathways involving 1,3-diphosphoglycerate and carbamoyl phosphate, e.g. glycolytic pathway and pyrimidine biosynthesis, by its ability to hydrolyze these substrates
-
-
?
additional information
?
-
-
possible physiological role for acylphosphatase activity may be regulation of metabolic pathways involving 1,3-diphosphoglycerate and carbamoyl phosphate, e.g. glycolytic pathway and pyrimidine biosynthesis, by its ability to hydrolyze these substrates
-
-
?
additional information
?
-
-
possible regulatory role of this enzyme in vivo on the calcium transport process by sarcoplasmic reticulum
-
-
?
additional information
?
-
-
acylphosphatase seems to have a regulatory function, controlling the concentrations of highly reactive compounds such as acyl phosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
acts specifically by splitting off the carboxyl phosphate bond
-
-
?
additional information
?
-
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
additional information
?
-
-
possible role of acylphosphatase in cell differentiation
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
no activity with 3-phosphoglycerate, phosphocreatine, DL-3-glycerophosphate, fructose 1,6-diphosphate, glucose 6-phosphate, fructose 6-phosphate, phosphoenolpyruvate, ATP, ADP, AMP, cyclic-AMP, 6-phosphogluconate phosphoserine
-
-
?
additional information
?
-
-
hydrolyzes phosphorylated intermediate formed during activity of membrane pump ATPase
-
-
?
additional information
?
-
-
hydrolyzes the beta-aspartylphosphate formed during the action of membrane pumps
-
-
?
additional information
?
-
-
hydrolyzes the beta-aspartylphosphate formed during the action of membrane pumps
-
-
?
additional information
?
-
-
acts specifically by splitting off the carboxyl phosphate bond
-
-
?
additional information
?
-
-
nucleolytic, ribonucleolytic and deoxyribonucleolytic, activity, exonucleolytic and endonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
additional information
?
-
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
additional information
?
-
-
role of acylphosphatase in pathologic situations
-
-
?
additional information
?
-
-
possible acyphosphatase involvement in the regulation of ion transport, and of calcium uptake in sarcoplasmic reticulum
-
-
?
additional information
?
-
-
nucleolytic activity of muscle and common type isoform acylphosphatase on RNA and DNA is possible physiological activity of these isoenzymes in the cell
-
-
?
additional information
?
-
-
possible role of acylphosphatase in cell differentiation
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
additional information
?
-
-
enzyme thought to participate in the regulation of glycolytic pathways and the synthesis of pyrimidine
-
-
?
additional information
?
-
-
acylphosphatase is active as a nuclease at pH ranging from 5.5 to 6.8 suggests that enzymes could play some role in apoptotic mechanisms
-
-
?
additional information
?
-
-
acylphosphatase increases the rate of Na+,K+-dependent ATP hydrolysis, acylphosphatase significantly stimulates the rate of ATP driven Na+ transport into sarcolemma vesicles: accelerrated hydrolysis of the phosphoenzyme may result in an enhanced activity of heart sarcolemma Na+,K+ pump, suggesting a potential role of acylphosphatase in the control of this active transport system
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
nucleolytic, ribonucleolytic and deoxyribonucleolytic, activity, exonucleolytic and endonucleolytic activity, in both muscle type, MT, and erythrocyte or common type, CT, isoenzymes
-
-
?
additional information
?
-
-
nucleolytic activity of muscle and common type isoform acylphosphatase on RNA and DNA is possible physiological activity of these isoenzymes in the cell
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
additional information
?
-
-
acylphosphatase is active as a nuclease at pH ranging from 5.5 to 6.8 suggests that enzymes could play some role in apoptotic mechanisms
-
-
?
additional information
?
-
-
acylphosphatase seems to have a regulatory function, controlling the concentrations of highly reactive compounds such as acyl phosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
acts specifically by splitting off the carboxyl phosphate bond
-
-
?
additional information
?
-
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
additional information
?
-
-
enzyme thought to participate in the regulation of glycolytic pathways and the synthesis of pyrimidine
-
-
?
additional information
?
-
-
enzyme thought to participate in the regulation of glycolytic pathways and the synthesis of pyrimidine
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
additional information
?
-
-
the partially folded ensemble of AcP displays enzymatic activity, but the early enzymatic activity of AcP is not contributed by the unfolded or native states
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
acts specifically by splitting off the carboxyl phosphate bond
-
-
?
additional information
?
-
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates
-
-
?
additional information
?
-
-
acts specifically by splitting off the carboxyl phosphate bond
-
-
?
additional information
?
-
-
possible role in preventing the intracellular accumulation of 1,3-diphosphoglycerate by catalyzing the hydrolysis of this substrate to 3-phosphoglycerate
-
-
?
additional information
?
-
-
acylphosphatase isoenzymes are probably involved in membrane ion transport, and glycolysis control
-
-
?
