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3.4.24.71: endothelin-converting enzyme 1

This is an abbreviated version!
For detailed information about endothelin-converting enzyme 1, go to the full flat file.

Word Map on EC 3.4.24.71

Reaction

Hydrolysis of the -Trp21-/-Val- bond in big endothelin to form endothelin 1 =

Synonyms

ECE, ECE-1, ECE-1b, ECE-3, ECE1, endothelin converting enzyme, endothelin converting enzyme-1, Endothelin-converting enzyme, endothelin-converting enzyme 1, endothelin-converting enzyme 1 (ECE-1), endothelin-converting enzyme I, endothelin-converting enzyme-1, endothelin-converting-enzyme-1, ET converting enzyme, hECE-1, More, sECE, solECE-1

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.71 endothelin-converting enzyme 1

pH Range

pH Range on EC 3.4.24.71 - endothelin-converting enzyme 1

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5.5 - 6.8
-
solECE-1 half-maximal activity at pH 5.7 and pH 6.7
5.7 - 7.3
-
native ECE-1, half-maximal activity at pH 6.2 and pH 7.0
5.8 - 7.8
-
about half-maximal activity at pH 5.8 and 7.8
6.5 - 7.2
-
active in a narrow range