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3.4.24.71: endothelin-converting enzyme 1

This is an abbreviated version!
For detailed information about endothelin-converting enzyme 1, go to the full flat file.

Word Map on EC 3.4.24.71

Reaction

Hydrolysis of the -Trp21-/-Val- bond in big endothelin to form endothelin 1 =

Synonyms

ECE, ECE-1, ECE-1b, ECE-3, ECE1, endothelin converting enzyme, endothelin converting enzyme-1, Endothelin-converting enzyme, endothelin-converting enzyme 1, endothelin-converting enzyme 1 (ECE-1), endothelin-converting enzyme I, endothelin-converting enzyme-1, endothelin-converting-enzyme-1, ET converting enzyme, hECE-1, More, sECE, solECE-1

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.71 endothelin-converting enzyme 1

Activating Compound

Activating Compound on EC 3.4.24.71 - endothelin-converting enzyme 1

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
captopril
-
solECE, activity 106.9%
chymostatin
-
-
E-64
-
-
K49-P1-20
i.e. N-terminal domain of Bothrops asper myotoxin II, 2fold enhancement of enzyme activity (maximal stimulation with 0.0001 mg/ml), activation concentration 50 (AC50) is 0.00192 mM
pepstatin A
-
-
PMSF
-
-
additional information
-