3.2.1.24: alpha-mannosidase

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For detailed information about alpha-mannosidase, go to the full flat file.

Word Map on EC 3.2.1.24

3.2.1.24

oligosaccharide

mannose

glycosidases

n-linked

swainsonine

hydrolases

mannans

n-glycans

concanavalin

alpha-fucosidase

xylanase

beta-n-acetylglucosaminidase

beta-d-galactosidase

beta-hexosaminidase

cellulase

endo-beta-n-acetylglucosaminidase

high-mannose

beta-d-glucosidase

galactomannans

1-deoxymannojirimycin

asparagine-linked

jack

beta-mannosidase

exoglycosidase

mannosylated

man9glcnac2

n-acetyl-beta-glucosaminidase

locust

beta-d-glucuronidase

complex-type

glucomannans

konjac

mannose-type

hemicellulases

glc3man9glcnac2

castanospermine

oligomannosides

alpha-d-galactosidase

alpha-d-glucosidase

mannose-rich

beta-xylosidase

lipid-linked

hexosaminidase

beta-n-acetylhexosaminidase

mannose-containing

hybrid-type

i-cell

mucolipidosis

oligomannose

analysis

cellulosome

diagnostics

medicine

Reaction

2-O-alpha-D-mannopyranosyl-D-mannopyranose

= 2 alpha-D-mannopyranose

Synonyms

1,2-alpha-D-mannosidase, 1,2-alpha-mannosidase, acid alpha-mannosidase, acidic alpha-mannosidase, alpha 1,2-mannosidase, Alpha mannosidase 6A8B, alpha-1,2-mannosidase, alpha-1,3 mannosidase, alpha-1,4 mannosidase, alpha-D-mannopyranosidase, alpha-D-mannosidase, Alpha-D-mannoside mannohydrolase, alpha-man, alpha-mann, alpha-mannosidase, alpha-mannosidase C, alpha-mannosidase E-II, alpha-mannosidase I, alpha-mannosidase IA, alpha-mannosidase II, alpha-mannosidase III, alpha1,2-mannosidase, AMAN, class II alpha-mannosidase, CpGH125, ER-alpha-mannosidase, ER-mannosidase II, exo-alpha-mannosidase, GH38 alpha-mannosidase, GH38 alpha-mannosidase II, GH38 class II alpha-mannosidase, GH38 enzyme, Golgi alpha-mannosidase II, Golgi mannosidase IA, Golgi mannosidase IB, Laman, Lysosomal acid alpha-mannosidase, lysosomal alpha-D-mannosidase, lysosomal alpha-mannosidase, Man1p, MAN2B1, Man2C1, Man2C1 alpha-mannosidase, ManA, mannanase, MGG_00994.6, More, neutral alpha-mannosidase, neutral/cytosol mannosidase, p-nitrophenyl-alpha-mannosidase, SpGH125, SpGH38, Ssa-man, SSO3006, TM1851, TMM, velmanase alfa

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.24 alpha-mannosidase

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Results	in table
24	Activating Compound
3495	AA Sequence
7	Application
1	CAS Registry Number
20	Cloned(Commentary)
10	Crystallization (Commentary)
1134	Disease/ Diagnostics
1	Expression
9	General Information
13	General Stability
32	IC50 Value
334	Inhibitors
46	kcat/KM [mM/s]
57	Ki Value [mM]
113	KM Value [mM]
58	Localization
76	Metals/Ions
91	Molecular Weight [Da]
116	Natural Substrates/ Products (Substrates)
339	Organism
2	Oxidation Stability
3	Pathway
38	PDB ID
89	pH Optimum
14	pH Range
20	pH Stability
24	Posttranslational Modification
56	Protein Variants
84	Purification (Commentary)
5	Reaction
4	Reaction Type
135	Reference
1	Renatured (Commentary)
104	Source Tissue
54	Specific Activity [micromol/min/mg]
12	Storage Stability
317	Substrates and Products (Substrate)
38	Subunits
104	Synonyms
1	Systematic Name
30	Temperature Optimum [°C]
5	Temperature Range [°C]
27	Temperature Stability [°C]
36	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 3.2.1.24 - alpha-mannosidase

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-20

Turbo cornutus

no loss of activity within 3 months

136025

0 - 4

Rattus sp.

60-70% loss of activity within 24 h

10 - 45

stable within

activity constant for 1 h

stable for 16 h

30 - 50

fully stable, no inactivation, no denaturation

698317

Triticum aestivum

half maximal activity

135986

Candida albicans

10% loss of activity after 2.5 h

135969

Rattus sp.

increasing activity up to

136007

Saccharomyces cerevisiae

stable for 5 min

136011

4 entries

Triticum aestivum

half maximal activity

135986

9 entries

Canavalia ensiformis

continual increase of activity up to

136015

2 entries