3.1.6.8: cerebroside-sulfatase

This is an abbreviated version!
For detailed information about cerebroside-sulfatase, go to the full flat file.

Word Map on EC 3.1.6.8

Reaction

a cerebroside 3-sulfate
+
H2O
=
a cerebroside
+
sulfate

Synonyms

ARS, arylsulfatase A, sulfatase, cerebroside, cerebroside sulfatase, cerebroside sulfate sulfatase, arylsulfatase E, ASA, Cerebroside-sulfatase, ARSA, AS-A, arylsulfatase-A

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.6 Sulfuric-ester hydrolases
                3.1.6.8 cerebroside-sulfatase

Crystallization

Crystallization on EC 3.1.6.8 - cerebroside-sulfatase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
aldehyde function and metal ion at the active site
crystal structure of mutant C69A in complex with p-nitrocatechol sulfate, Protein Data Bank: 1E1Z and 1E2S, and crystal structure of mutant C69S in complex with p-nitrocatechol sulfate, Protein Data Bank: 1E33 and 1E3C
crystallisation of enzyme at pH 5.4 in a new monoclinic crystal form, at pH 6.5-6.7, tetragonal crystals are obtained.
-
crystal structure of mutant C69A a nd C69S in complex with p-nitrocatechol sulfate