3.1.6.8: cerebroside-sulfatase
This is an abbreviated version!
For detailed information about cerebroside-sulfatase, go to the full flat file.
Word Map on EC 3.1.6.8
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3.1.6.8
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metachromatic
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leukodystrophy
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sulfatide
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medicine
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lysosomal
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asa
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demyelinate
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sural
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pseudodeficiency
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nitrocatechol
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sulfatases
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molecular biology
- 3.1.6.8
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metachromatic
- leukodystrophy
- sulfatide
- medicine
- lysosomal
- asa
-
demyelinate
-
sural
-
pseudodeficiency
- nitrocatechol
-
sulfatases
- molecular biology
Reaction
Synonyms
ARS, ARSA, arylsulfatase A, arylsulfatase E, arylsulfatase-A, AS-A, ASA, cerebroside sulfatase, cerebroside sulfate sulfatase, Cerebroside-sulfatase, sulfatase, cerebroside
ECTree
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Activating Compound
Activating Compound on EC 3.1.6.8 - cerebroside-sulfatase
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bis(monoacylglycero) phosphate
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at a relative concentration of 30 mol% the lipid stimulates the reaction rate by a factor of 3.4
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dolichol
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at a relative concentration of 30 mol% the lipid stimulates the reaction rate by a factor of 2.7
phosphatidic acid
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at a relative concentration of 30 mol% the lipid stimulates the reaction rate by a factor of 3.1
Protein factor
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activator protein stimulates lipid soluble substrates more than water soluble substrates
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Protein factor
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enzyme cleaves cerebroside sulfates only in the presence of either specific detergent, e.g. taurodeoxycholate or human activator protein
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Protein factor
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no requirement for activators when acting on cerebroside sulfate
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Protein factor
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degradation of sulfosphingolipids and sulfoglycerolipids with or without activator protein, critical micellar concentration important
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taurodeoxycholate
Blaberus fuscus
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acidic form of enzyme is active without taurodeoxycholate
taurodeoxycholate
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enzyme cleaves cerebroside sulfates only in the presence of either specific detergent, e.g. taurodeoxycholate or human activator protein
taurodeoxycholate
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acidic form of enzyme is active without taurodeoxycholate
taurodeoxycholate
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acidic form of enzyme is active without taurodeoxycholate
taurodeoxycholate
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acidic form of enzyme is active without taurodeoxycholate
taurodeoxycholate
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acidic form of enzyme is active without taurodeoxycholate
taurodeoxycholate
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acidic form of enzyme is active without taurodeoxycholate
taurodeoxycholate
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acidic form of enzyme is active without taurodeoxycholate
taurodeoxycholate
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acidic form of enzyme is active without taurodeoxycholate
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
Blaberus fuscus
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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phosphatidylinositol and phosphatidylserine have no effect on the rate of sulfatide hydrolysis
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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additional information
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low ionic strength, about 0.01 M buffer activity without activator protein or detergent
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