3.1.6.8: cerebroside-sulfatase
This is an abbreviated version!
For detailed information about cerebroside-sulfatase, go to the full flat file.
Word Map on EC 3.1.6.8
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3.1.6.8
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metachromatic
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leukodystrophy
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sulfatide
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medicine
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lysosomal
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asa
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demyelinate
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sural
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pseudodeficiency
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nitrocatechol
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sulfatases
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molecular biology
- 3.1.6.8
-
metachromatic
- leukodystrophy
- sulfatide
- medicine
- lysosomal
- asa
-
demyelinate
-
sural
-
pseudodeficiency
- nitrocatechol
-
sulfatases
- molecular biology
Reaction
Synonyms
ARS, ARSA, arylsulfatase A, arylsulfatase E, arylsulfatase-A, AS-A, ASA, cerebroside sulfatase, cerebroside sulfate sulfatase, Cerebroside-sulfatase, sulfatase, cerebroside
ECTree
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Molecular Weight
Molecular Weight on EC 3.1.6.8 - cerebroside-sulfatase
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140000
49000
50000
54000
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in the liver samples of control and ethanol treated rats, Western blot analysis
55000
62000
63000
66000
49000
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aggregation to tetramer at higher concentrations around pH 5, 2 * 49000, 2 * 55000
50000
enzyme is synthesized as a preprotein with 507 amino acids, the mature protein has 489 amino acids with a calculated mass of 52000
50000
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in the liver samples of control and ethanol treated rats, Western blot analysis
55000
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aggregation to tetramer at higher concentrations around pH 5, 2 * 49000, 2 * 55000
-
copurification with beta-galactosidase, both enzymes aggregate into macromolecular complexes at pH 4 and disaggregate at pH 8, SDS-PAGE