1.3.1.124: 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
This is an abbreviated version!
For detailed information about 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], go to the full flat file.
Word Map on EC 1.3.1.124
Reaction
Synonyms
2,4-dienoyl coenzyme A reductase, 2,4-dienoyl-CoA reductase, 4-enoyl-CoA reductase, DCR, DECR, DECR1, DECR2, DELTA2,DELTA4-dienoyl-CoA reductase, More, pDCR, SPS19
ECTree
1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]Advanced search results
results (
results (Cloned
Cloned on EC 1.3.1.124 - 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
CLONED (Commentary) 
ORGANISM
UNIPROT
LITERATURE
creation of a DECR-deficient mouse line, fasted Decr-/- mice display increased serum acylcarnitines, especially decadienoylcarnitine, a product of the incomplete oxidation of linoleic acid (C18:2), urinary excretion of unsaturated dicarboxylic acids, and hepatic steatosis, wherein unsaturated fatty acids accumulate in liver triacylglycerols, metabolically challenged Decr-/- mice turn on ketogenesis, but unexpectedly develop hypoglycemia
-
expressed in Escherichia coli
expression of a highly active truncated soluble protein in Escherichia coli
overexpression of His-tagged truncated wild-type and of mutant enzymes in Escherichia coli strain BL21(DE3), expression as soluble protein, except for mutant D117A
-
overexpression of His-tagged wild-type and mutant enzymes in Escherichia coli strain BL21(DE3), expression of selenomethionine enzyme in Escherichia coli strain B834(DE3)
-
