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1.3.1.124: 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

This is an abbreviated version!
For detailed information about 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], go to the full flat file.

Word Map on EC 1.3.1.124

Reaction

a (2E)-2-enoyl-CoA
+
NADP+
=
a (2E,4E)-2,4-dienoyl-CoA
+
NADPH
+
H+

Synonyms

2,4-dienoyl coenzyme A reductase, 2,4-dienoyl-CoA reductase, 4-enoyl-CoA reductase, DCR, DECR, DECR1, DECR2, DELTA2,DELTA4-dienoyl-CoA reductase, More, pDCR, SPS19

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

Systematic Name

Systematic Name on EC 1.3.1.124 - 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

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SYSTEMATIC NAME
IUBMB Comments
(3E)-3-enoyl-CoA:NADP+ 4-oxidoreductase
This enzyme, characterized from eukaryotic organisms, catalyses the reduction of either (2E,4E)-2,4-dienoyl-CoA or (2E,4Z)-2,4-dienoyl-CoA to (3E)-3-enoyl-CoA. The best substrates for the enzyme from bovine liver have a chain-length of 8 or 10 carbons. Mammals possess both mitochondrial and peroxisomal variants of this enzyme. cf. EC 1.3.1.34, 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing].