1.1.1.283: methylglyoxal reductase (NADPH)

This is an abbreviated version!
For detailed information about methylglyoxal reductase (NADPH), go to the full flat file.

Word Map on EC 1.1.1.283

Reaction

(S)-lactaldehyde
+
NADP+
=
2-oxopropanal
+
NADPH
+
H+

Synonyms

1.1.1.78, AKR, aldo-keto reductase, D-lactaldehyde dehydrogenase, Gre2, GRE2 gene product, GRE2/YOL151W, Gre2p, MeGR, methylglyoxal reductase, methylglyoxal reductase (NADPH dependent), methylglyoxal/isovaleraldehyde reductase, More, NADPH-dependent methylglyoxal reductase, SakR1, YGL039w1, YGL039w2, YOL151W, YOL151w gene product

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.283 methylglyoxal reductase (NADPH)

Purification

Purification on EC 1.1.1.283 - methylglyoxal reductase (NADPH)

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PURIFICATION/commentary
ORGANISM
UNIPROT
LITERATURE
recombinant His6-tagged wild-type and mutant enzymes from Escherichia coli strain BL21(DE3) by nickel affinity chromatography and gel filtration, followed by ultrafiltration
-
similar enzyme with NADPH-requirement for methylglyoxal reduction, that is inactive with NAD+, NADH and NADP+
-
two methylglyoxylate reductases: MGR I and MGR II, similar enzyme with NADPH-requirement for methylglyoxal reduction, that is inactive with NAD+, NADH and NADP+
-