1.1.1.283: methylglyoxal reductase (NADPH)

This is an abbreviated version, for detailed information about methylglyoxal reductase (NADPH), go to the full flat file.

Reaction

(S)-lactaldehyde
+
NADP+
=
2-oxopropanal
+
NADPH
+
H+

Synonyms

1.1.1.78, AKR, aldo-keto reductase, D-lactaldehyde dehydrogenase, Gre2, GRE2 gene product, GRE2/YOL151W, Gre2p, MeGR, methylglyoxal reductase, methylglyoxal reductase (NADPH dependent), methylglyoxal/isovaleraldehyde reductase, More, NADPH-dependent methylglyoxal reductase, SakR1, YGL039w1, YGL039w2, YOL151W, YOL151w gene product

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.283 methylglyoxal reductase (NADPH)

Specific Activity

Specific Activity on EC 1.1.1.283 - methylglyoxal reductase (NADPH)

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0048
-
at 25C, in 50 mM HEPES (pH 7.0)
0.0053
-
at 25C, in 50 mM HEPES (pH 7.0)
0.0094
-
at 25C, in 50 mM HEPES (pH 7.0)
0.038
-
1 mM acetaldehyde as substrate
0.047
-
1 mM crotonaldehyde as substrate; 1 mM isatin as substrate
0.048
-
1 mM dihydroxyacetone as substrate
0.109
-
50 mM D-glucose as substrate
0.211
-
1 mM ninhydrin as substrate
0.225
-
1 mM succinic semialdehyde as substrate
0.24
-
50 mM D-galactose as substrate
0.364
-
50 mM L-arabinose as substrate
0.373
-
1 mM diacetyl as substrate
0.507
-
1 mM DL-glyceraldehyde as substrate
0.641
-
1 mM isopentaldehyde as substrate
0.651
-
1 mM benzaldehyde as substrate
0.66
-
50 mM D-xylose as substrate
0.83
-
enzyme MGR I
0.96
substrate methylglyoxal, pH 6.0, 25C
1.072
-
1 mM 3-nitrobenzaldehyde as substrate
1.091
-
1 mM 4-nitrobenzaldehyde as substrate
1.1
substrate p-anisaldehyde, pH 6.0, 25C
1.206
-
1 mM 2-nitrobenzaldehyde as substrate
1.278
-
1 mM methylglyoxal as substrate
2.1
substrate octanal, pH 6.0, 25C; substrate valeraldehyde, pH 6.0, 25C
3
substrate heptanal, pH 6.0, 25C
3.2
substrate methyl glyoxal, pH 6.0, 25C
3.3
substrate isovaleraldehyde, pH 6.0, 25C
4.2
substrate isovaleraldehyde, pH 6.0, 25C
4.5
substrate p-anisaldehyde, pH 6.0, 25C
5.3
substrate octanal, pH 6.0, 25C
5.9
substrate valeraldehyde, pH 6.0, 25C
6.9
substrate heptanal, pH 6.0, 25C
7.77
-
enzyme MGR II