1.1.1.283: methylglyoxal reductase (NADPH)

This is an abbreviated version!
For detailed information about methylglyoxal reductase (NADPH), go to the full flat file.

Word Map on EC 1.1.1.283

Reaction

(S)-lactaldehyde
+
NADP+
=
2-oxopropanal
+
NADPH
+
H+

Synonyms

1.1.1.78, AKR, aldo-keto reductase, D-lactaldehyde dehydrogenase, Gre2, GRE2 gene product, GRE2/YOL151W, Gre2p, MeGR, methylglyoxal reductase, methylglyoxal reductase (NADPH dependent), methylglyoxal/isovaleraldehyde reductase, More, NADPH-dependent methylglyoxal reductase, SakR1, YGL039w1, YGL039w2, YOL151W, YOL151w gene product

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.283 methylglyoxal reductase (NADPH)

Specific Activity

Specific Activity on EC 1.1.1.283 - methylglyoxal reductase (NADPH)

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0048
-
at 25C, in 50 mM HEPES (pH 7.0)
0.0053
-
at 25C, in 50 mM HEPES (pH 7.0)
0.0094
-
at 25C, in 50 mM HEPES (pH 7.0)
0.038
-
1 mM acetaldehyde as substrate
0.047
-
1 mM crotonaldehyde as substrate; 1 mM isatin as substrate
0.048
-
1 mM dihydroxyacetone as substrate
0.109
-
50 mM D-glucose as substrate
0.211
-
1 mM ninhydrin as substrate
0.225
-
1 mM succinic semialdehyde as substrate
0.24
-
50 mM D-galactose as substrate
0.364
-
50 mM L-arabinose as substrate
0.373
-
1 mM diacetyl as substrate
0.507
-
1 mM DL-glyceraldehyde as substrate
0.641
-
1 mM isopentaldehyde as substrate
0.651
-
1 mM benzaldehyde as substrate
0.66
-
50 mM D-xylose as substrate
0.83
-
enzyme MGR I
0.96
A0A0E4AX59, A0A0E4AY21
substrate methylglyoxal, pH 6.0, 25C
1.072
-
1 mM 3-nitrobenzaldehyde as substrate
1.091
-
1 mM 4-nitrobenzaldehyde as substrate
1.1
A0A0E4AX59, A0A0E4AY21
substrate p-anisaldehyde, pH 6.0, 25C
1.206
-
1 mM 2-nitrobenzaldehyde as substrate
1.278
-
1 mM methylglyoxal as substrate
2.1
A0A0E4AX59, A0A0E4AY21
substrate octanal, pH 6.0, 25C; substrate valeraldehyde, pH 6.0, 25C
3
A0A0E4AX59, A0A0E4AY21
substrate heptanal, pH 6.0, 25C
3.2
A0A0E4AX59, A0A0E4AY21
substrate methyl glyoxal, pH 6.0, 25C
3.3
A0A0E4AX59, A0A0E4AY21
substrate isovaleraldehyde, pH 6.0, 25C
4.2
A0A0E4AX59, A0A0E4AY21
substrate isovaleraldehyde, pH 6.0, 25C
4.5
A0A0E4AX59, A0A0E4AY21
substrate p-anisaldehyde, pH 6.0, 25C
5.3
A0A0E4AX59, A0A0E4AY21
substrate octanal, pH 6.0, 25C
5.9
A0A0E4AX59, A0A0E4AY21
substrate valeraldehyde, pH 6.0, 25C
6.9
A0A0E4AX59, A0A0E4AY21
substrate heptanal, pH 6.0, 25C
7.77
-
enzyme MGR II