2.7.7.14: ethanolamine-phosphate cytidylyltransferase
This is an abbreviated version!
For detailed information about ethanolamine-phosphate cytidylyltransferase, go to the full flat file.
Word Map on EC 2.7.7.14
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2.7.7.14
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phosphatidylethanolamine
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phospholipid
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cdp-ethanolamine
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diacylglycerols
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kennedy
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cdp-choline
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ctp:phosphocholine
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phosphocholine
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3hethanolamine
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ptdetn
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ethanolaminephosphotransferase
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14cethanolamine
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drug development
- 2.7.7.14
- phosphatidylethanolamine
- phospholipid
- cdp-ethanolamine
- diacylglycerols
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kennedy
- cdp-choline
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ctp:phosphocholine
- phosphocholine
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3hethanolamine
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ptdetn
- ethanolaminephosphotransferase
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14cethanolamine
- drug development
Reaction
Synonyms
CTP-phosphoethanolamine cytidylyltransferase, CTP:ethanolaminephosphate cytidylyltransferase, CTP:phosphoethanolamine CT, CTP:phosphoethanolamine cytidylyltransferase, CTP:phosphoethanolamine cytidylyltransferase gene, cytidylyltransferase, ethanolamine phosphate, ECT, ET, ethanolamine phosphate cytidylyltransferase, ethanolamine-phosphate cytidylyltransferase, Pcyt2, Pcyt2alpha, Pcyt2beta, PECT1, phosphoethanolamine cytidyltransferase, phosphoethanolamine cytidylyltransferase, phosphorylethanolamine transferase, Tb11.01.5730
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Inhibitors
Inhibitors on EC 2.7.7.14 - ethanolamine-phosphate cytidylyltransferase
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1-Aminoethylphosphonate
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inhibitory power stimulated by Mg2+; noncompetitive to phosphorylethanolamine
2-aminoethylphosphonate
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competitive to phosphorylethanolamine; inhibitory power stimulated by Mg2+
3-Aminopropylphosphonate
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competitive to phosphorylethanolamine; inhibitory power stimulated by Mg2+
Sphingosine/phosphatidylcholine vesicles
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inhibit cytosolic and purified enzyme
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additional information
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overactivation of the NMDA receptor in neurons inhibits the enzyme, membrane damage by NMDA receptor is preceeded by inhibition of phospholipid synthesis
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phosphoethanolamine methyl-analogues
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weak competitive inhibitors of Pcyt2
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phosphoethanolamine methyl-analogues
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weak competitive inhibitors of Pcyt2
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phosphoethanolamine methyl-analogues
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weak competitive inhibitors of Pcyt2
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phosphoethanolamine methyl-analogues
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weak competitive inhibitors of Pcyt2
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